Bioscience, Biotechnology, and Biochemistry, 2006 Oct;70(10):2508-14Royal jelly (RJ) has diverse physiological and pharmacological functions…Oral administration of RJ to normal female mice for 9 weeks increased the ash content of their tibiae. DNA microarray analysis revealed significant changes in gene expression related to extracellular matrix formation when the femurs of mice fed RJ were analyzed…
These data suggest that RJ as a whole or some of its individual components stimulates production of type I collagen and other activities for bone formation through action on osteoblasts.
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