Antinociceptive Activity of Natural Honey in Thermal-Nociception Models in Mice
Phytotherapy Research, 7 Dec 2006
Abstract: Several honey samples of Pakistani origin have been analysed for their effect on nociception. Among the tested samples, Acacia honey showed most effective dose-dependent antinociceptive activity which was significantly different from the untreated group in tail-flick and paw-withdrawal tests (p < 0.01 and p < 0.003), respectively… The absence of antinociceptive activity in simulated honey (which contained fructose, glucose, maltose and sucrose representing the major constituents of honey) indicated that the active principle(s) might be present in minor constituents of honey.
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