Study: Some Royal Jelly Products Contain Little 10-HDA

Comparison of UPLC and HPLC for Determination of Trans -10-Hydroxy-2-Decenoic Acid Content in Royal Jelly by Ultrasound-Assisted Extraction with Internal Standard
Journal Chromatographia, Volume 66, Numbers 3-4, 2007

Abstract: The ultra performance liquid chromatography (UPLC) and high performance liquid chromatography (HPLC) method was developed and compared to detect the trans-10-hydroxy-2-decenoic acid (10-HDA) content in royal jelly cream and lyophilized powder…

The concentration of 10-HDA ranges from 1.26 to 2.25% for pure royal jelly cream samples and 3.01–6.26% for royal jelly lyophilized powder samples. For 30 royal jelly products, the 10-HDA content varied from no detectable to 1.005%.