AMP N1-oxide Potentiates Astrogenesis by Cultured Neural Stem/Progenitor Cells Through STAT3 ActivationBiomedical Research, Vol. 28, pp.295-299 (2007)
We earlier identified adenosine monophosphate (AMP) N1-oxide as a unique compound of royal jelly (RJ) that induces neurite outgrowth from cultured rat pheochromocytoma PC12 cells.
In the present study, the effects of AMP N1-oxide on the proliferation and/or differentiation of cultured neural stem/progenitor cells (NSCs) were examined…
These results suggest that AMP N1-oxide is one of the components that facilitates astrogenesis by NSCs through activation of STAT3…
Our present results suggest that AMP N1-oxide may be a good tool for protection against and therapy for certain brain injuries, because astrocytes play important roles in brain development and the response to injury…
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