Study of Propolis Composition May Lead to Standardization

Effect of the Brazilian propolis extracts against bloodstream trypomastigotes of Trypanosoma cruzi after 1 day of treatment at 4°C. The bars represent the standard deviation of at least three independent experiments.

Brazilian Propolis: Correlation Between Chemical Composition and Antimicrobial Activity
Evidence-based Compl. and Alt. Medicine, 2008, Volume 5, Number 3 Pp. 317-324

The chemical composition of ethanol extracts from samples of Brazilian propolis (EEPs) determined by HPLC and their activity against Trypanosoma cruzi, Staphylococcus aureus, Streptococcus pneumoniae, Klebisiella pneumoniae, Candida albicans, Sporothrix schenckii and Paracoccidioides brasiliensis were determined…

The present study reinforces the relevance of PCUM and derivatives, especially prenylated ones and also of caffeolyquinic acids, on the biological activity of Brazilian propolis…

As typical of Brazilian propolis (2), most of the compounds present in the EEPs were phenolics, being present in high content hydroxycinnamic acids, such as PCUM and CAF and their prenylated derivatives…

The association of the chemical composition of propolis from different geographic regions with biological activities lead to the identification of active principles, a fundamental tool to achieve standardization of this bee product…