Royal Jelly Component May Have Antihypertensive Activity

Expression of Apalbumin1 of Apis cerana cerana in the Larvae of Silkworm, Bombyx mori
J. Agric. Food Chem, 2008, 56 (20), pp 9464–9468

Royal jelly (RJ) is a thick, milky material produced by both the hypopharyngeal and the mandibular glands of nurse honeybees. The main proteins of RJ, named apalbumins or major royal jelly proteins (MRJPs), have multiple biological functions. Apalbumin1 is the most abundant glycoprotein of RJ.

In this study, Bacmid-apalbumin1 was constructed for Apis cerana cerana using the newly established Bac-to-Bac/BmNPV baculovirus expression system (BES)…

The peptide Ile-Phe was identified from trypsin production of rAccapalbumin1. Such a peptide has been reported to have an antihypertensive ability. Our results have therefore potential applications in biomedical research and open new perspectives for the study of apalbumins.