Honey Helps Heal Radiotherapy-Impaired Wounds

Using Leptospermum Honey to Manage Wounds Impaired By Radiotherapy: A Case Series
Ostomy Wound Management, 2009 Jan;55(1):38-47

Radiation-induced tissue injury and wounds with radiation-impaired healing are traumatic for patients and challenging for their caregivers. Standardized management approaches do not exist.

The effect of Leptospermum honey as a primary dressing for managing these wounds was assessed in four patients (age range 63 to 93 years) who had previously undergone radiotherapy that left them with fragile friable areas of damaged skin that did not respond to conventional treatment.

Compromised areas involved the neck, cheek, groin/perineum, and chest. In patients 1 and 2, after topical application of honey via hydrofiber rope and nonadhesive foam, respectively, improvements in the size and condition of wound/periwound area and a reduction in pain were noted before death or loss to follow-up.

After including honey in the treatment regimen of patients 3 and 4, complete healing was noted in 2.5 weeks (with honey and paraffin) and 6 weeks (with honey-soaked hydrofiber rope), respectively. No adverse events were reported. Honey as an adjunct to conventional wound/skin care post radiation therapy shows promise for less painful healing in these chronic wounds. Prospective, randomized, controlled clinical studies are needed to confirm these observations…

Discussion:

Four patients with radiotherapy-impaired wounds and compromised skin received care that included medical grade honey. In all cases, a change from conventional dressings to the topical application of honey was followed by a noticeable improvement in healing. It is not possible to report complete healing in all examples because Patient 1 (Mr. G) died and Patient 2 (Ms. H) was lost to follow-up but the latter reported a noticeable reduction in pain once honey was introduced. No adverse events were observed and even though Patient 3 (Ms. J) had type 2 diabetes, daily honey applications to her wound had no adverse effect on her blood sugar levels. All patients readily accepted honey as a dressing for their wounds…