Food Chem, 2014 Jan 15;143:362-6
Antitumour potential of honey is attributed to its excellent
antioxidant activity which in turn depends on the geographical origin. The
present study focuses on exploration of antioxidant and antitumour potential as
well as total phenolic contents (TPC) of 58 Pakistani honeys involving
spectrochemical techniques and potato disk assay. Agrobacterium tumefaciens was
used to induce tumours in potato disks.
All analysed honey samples exhibited
1.33±0.00-155.16±0.98mg/100g of TPC, 50% 2,2-diphenyl picryl hydrazyl (DPPH)
inhibition, ⩾7.36±0.43-39.86±2.34mg/100g qurecitin equivalent
antioxidant contents, ⩾13.69±0.91-65.50±1.37mg/100g
ascorbic acid equivalent antioxidant contents, 64.65±0.43-1780.74±11.79mM
ferric reducing antioxidant power and 60% peroxide inhibition. Antitumour
activity observed for 43 natural and 10 commercial samples was ⩾20%.
Two samples from Faisalabad region showed 87.50±5.50% and 79.00±5.56%
antitumour activity which were reference standard. It was concluded that Pakistani honeys possessed excellent
antioxidant and antitumour potential overall.
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