Caffeic Acid Phenethyl Ester: Its Protective Role Against
Certain Major Eye Diseases
J Ocul Pharmacol Ther, 2014 Aug 6
Abstract As an effective compound found mainly in the honeybee product propolis, caffeic acid phenethyl ester (CAPE) has been commonly utilized as a medicine and remedial agent, in a number of countries. Specifically, it might inhibit nuclear factor kappa B at micromolar concentrations and demonstrate antioxidant, antineoplastic, antiproliferative, cytostatic, antiviral, antibacterial, antifungal, and anti-inflammatory features.
Abstract As an effective compound found mainly in the honeybee product propolis, caffeic acid phenethyl ester (CAPE) has been commonly utilized as a medicine and remedial agent, in a number of countries. Specifically, it might inhibit nuclear factor kappa B at micromolar concentrations and demonstrate antioxidant, antineoplastic, antiproliferative, cytostatic, antiviral, antibacterial, antifungal, and anti-inflammatory features.
This review article
summarizes the recent progress regarding the favorable effects of CAPE on a number
of eye disease models, including cataract and posterior capsule opacification,
corneal diseases, retina and optic nerve-related diseases, ischemia/reperfusion
injury of retina, inflammation and infection-related diseases.
CAPE has been
found to exhibit promising efficacy, with minimal adverse effects, in animal
and cell culture studies of several eye diseases.
No comments:
Post a Comment