Antigiardial activity of glycoproteins and glycopeptides
from Ziziphus honey
Nat Prod Res. 2015 Jan 14:1-3
Natural honey contains an array of glycoproteins,
proteoglycans and glycopeptides. Size-exclusion chromatography fractionated
Ziziphus honey proteins into five peaks with molecular masses in the range from
10 to >200 kDa. The fractionated proteins exhibited in vitro activities
against Giardia lamblia with IC50 values ≤ 25 μg/mL. Results indicated that
honey proteins were more active as antiprotozoal agents than metronidazole.
This study indicated the potential of honey proteins and peptides as novel
antigiardial agents.
No comments:
Post a Comment