Apimedica: Treating Ophthalmic Disorders with Bee Venom Therapy - 几种眼科疾病的蜂毒治疗

Treatment of Few Ophthalmic Diseases by Honey Bee Venom (HB)

Apimondia Apimedica-Apiquality International Forum 

Oct. 22-25, 2012

Zhenjiang, China

1- B. Kaviani Vahid Pharm.D.

No. 121, DPl Plasma Center, South of Ghiasi Hospital, Taleghani St., Valiasr Town, P.C.: 1373658153 Tehran, Iran

2- M. Pourmojib M.D. (Gynecologist)

Yas building, First alley, Haft tir St., Saeedi Sq., P.O. Box: 37100617537, Ghom, Iran

3- M. Mashayekhi, Bsc

Iranian Research for science and Technology (IROST), Sh. Ehsanabad Khalese Road) P.O. Box: 13135-115, Tehran, Iran.

Using Honey Bee Venom for treatment of some auto-immune disease now is popular in apitherapists. The bee hive product and specially its venom have prominent position within natural toxins. During past decades natural remedies became more popular than before. This has different reasons. One of them was severe side effects of common medicines within the market and the other in this paper 5 case report of this treatment is described.

Introduction

There are a lot of eye problems which could make someone to seek for a treatment. 

The following 3 disease has been treated by this method. 

1-  Uveitis

Inflammation of the middle layer of the eye, termed the “uvea”. Uveitis may develop following eye trauma or surgery, in association with diseases which affect other organs in the body, or may be a condition isolated to the eye itself. Severe and permanent visual loss can result from uveitis.  

2-  Blurred vision due to MS 

This blurred vision could be due to an immune based disease such Multiple Sclerosis.

Optic nerve problems due to a systemic degenerative auto – immune disease such as MS may happen in related patients.

3- Sudden blurred vision

In normal subjects without any diagnosis or back ground of autoimmune disease sudden blurred vision may happen.

Materials and Method

In this treatment volunteer patients who were treated previously with routine medications were selected by a physician. Before starting the treatment the patient is asked to read the treatment protocol carefully and sign out the inform consent. In the BVT (Bee Venom Therapy) protocol all medications should be discontinued and Para-clinical tests such as Clearance of Creatinine, Serum Cortisol and Titration of IgG are performed.

Controlled bee hives in which bees were naturally feed were specified by an experienced beekeeper. The mother bee hives were kept as far as possible from city pollution and farms’ poison spraying. In order to carry the required live bees to the surgery in the middle of town an especial isolated queen’s hive was used. This new bee hive has been patented by Prof.  J. Pourasghar in Iran.

Patients Case Reports

a- A 22 years old girl with MS diagnosis referred to us. She had symptoms such as blurred vision, diplopia. She had to wear an eye glasses due to an ophthalmologist diagnosis after one month of her MS diagnosis. She had also parasthesia in her feet which would expand after high stresses.

b- A 28 years old lady the mother of two children who had been diagnosed with Multiple Sclerosis. Complained mostly from eye problems together with phobia from jumping and height.  

c- A 38 years old lady who had been diagnosed with Uveitis whose job was a shooting trainer faced with sudden symptoms such as redness and pain in her left eye.

d- A 46 years old male without any previous ocular problems had a sudden blurred vision.

After referring to 3 ophthalmologists and performing different clinical and Para-clinical tests such as angiography from retina’s vessels, Optic Coherence Tomography (OCT) and Ocular pressure had been examined. Those diagnoses differed from need to use eye glasses for Myopa, increasing the yellow spot on the retina, and accumulation of water behind the retina to Migraine. The most optimistic forecast for solving the blurred vision problem was at least 1 year time period. 

e-   A 32 year old newly married female with the diagnosis of MS and the symptoms of severe blurred vision after a little dispute and tension. This patient The 26 year old MS diagnosed married lady who had been recommended not to be pregnant which may worsen her disease situation.

Para-clinical Tests

Before applying the Bee Venom Therapy, the patients were asked to perform few Para-clinical tests such as titration of IgG, morning serum Cortisol and functional tests for kidneys.

The summary of paraclinical tests before treatment is shown in Table 1.

To follow up the situation of patient’s paraclinically, the patients were asked to perform 4 tests such as IgG, IgG4, Total Protein (TP), and Morning Serum Cortisol within each 4 months time period.

The summary of paraclinical tests after treatment is shown in Table 2.

Applying Honey Bee Sting in Patients

At the first step after checking the first Para-clinical test results prior to apply the Sting test we should make sure that the presented treatment protocol is observed carefully. It means if the patient was in her menses period she was asked to post pone the BVT session till she had even no spotting. 

For the start session 4 stings were applied after the first sting test from live bee of a controlled bee hive. The first sting was applied preferably at the lower limbs and the stinger would be removed as fast as possible. 

Then 4 bee stings were applied on the eye points based upon the shiatsu pressure points.  At the continued sessions the stings applied on the area defined on the other points regularly with the exception of do not using the bee sting in place that was already swollen by previous stings. 

Results 

Clinically all patients have been examined thoroughly and following results obtained: In first patient with MS not only she took off her eye glasses which surprised her ophthalmologist, but also the blurred vision and lower limbs parasthesia especially in her feet has been diminished. This young girl during this treatment succeed in the conquer in university and has got 2 medallion positions in her hobby sports. In second lady with MS she not only regains all of her vision abilities but also she has no phobia from height or jump.

3- In third patient with Uvietis the pain of left eye cornea has been finished and the blurred vision has been decreased and time to time after severe stress may happen but not as it was before treatment.

4- The 46 years old guy with a sudden eye problem, whom the ophthalmologists anticipate at least 1 year time period for his recovery, became completely cleared in vision after applying 4 live bee stings in 2 sessions nearby his eyes. The ophthalmologist was surprised after his examination of clear vision with no need to any eye glasses or further medications. In this patient due to short term illness and short time of recovery there is no Para-clinical comparison before and after treatment.

5- The 26 year old newly married lady MS diagnosed after one and half a year period time became symptoms free. Therefore we recommend her to go for pregnancy. Now she has a son and due to her job in school time to time she may has a dispute but no blurred vision will happen again.

The summary of applying Honey Bee Venom for the mentioned patients are given in Table 3

Patients	IgG4	IgG	TP	Serum Cortisol 8AM
1	84	7888	7.8	13.3
2	36	946	6.9	9.2
3	16.92	1253	7.2	6.4
4	42	1700	7.5	5.6

Table 1: The Para-clinical test results before starting BVT

Patients	IgG4	IgG	TP	Serum Cortisol 8 AM
1	172	1448	8.1	21.2
2	72	858	7.1	19.8
3	56.82	1282	7.8	18.3
4	162.5	15.89	7.4	11.2

Table 2: The Para-clinical test results after BVT

Patient No.	Gender	Age	Eye Problem	Total Stings	Maximum Bee Stings in one Session	No. of BVT Sessions	Duration of Treatment
1	F	22	MS	380	30	36	3 Years
2	F	28	MS	311	80	40	3 Years
3	F	38	Uveites (Iritis)	841	60	31	2 Years
4	M	46	Blurred Vision	4	2	2	4 Weeks
5	F	32	Diplopia	44	10	8	4 Months

Discussion 

Due to protein based characteristics of Bee Venom and its water solubility, in order to care more for its depletion from the body of patients it’s necessary to check out the functional tests of the kidney before commencing Bee Venom Therapy (BVT). 

In this regard for more safety of patient in applying bee venom a complete test for patient’s kidneys is performed.

In order to use live honey bees we should use the controlled bee hives.  

 The main reason for applying a controlled bee hive was to observe the most intact bee hive products (organic product) for the patients. 

As far as we believe not only the HBV could not reconstruct the Meylin Shield over the nerves nor could substitute instead of the damaged parts of Myelin, observance of the appropriate life style is so important for the patients.

The mentioned protocol is structured in this purpose and it has following instructions such as:  - In order to help the different organs for good defecation, the patient should have a complete rest (at least 4 hours) before mid-night).

-  Taking massage under the water shower before 8 A.M. early every morning. 

-  Drinking the water as a medication (more than 3 liters within a day)

-  Good defecation (more than 3 times of bowel moving within a day due to instruction of  Avicenna 1)

-  Having increase sport time within a week

The nutrition of patients plays a noticeable role in their recovery. Based up on the physiology of the human beings’ teeth, there is a recommendation to use the required meat not more than 1/8 of their total food. 

Comparison of paraclinical results of the patients before and after treatment shows a rise in the titer of IgG4 as the main anti body against HBV. The IgG4 antibody is one of four subclasses of IgG which in spite of the other subclasses has good effects in patient’s body.

The nutrition of patients was checked by means of Total Protein (TP) Test. In order to a valuable reconstruction of the nerves shield, the blood stream of patients should be enriched from different essential amino acids. In this reason the raises of TP could be so important to improve the patients’ shows the better nutrition of patient.

Bee venom Therapy plus appropriate nutrition, raises the serum Cortisol level at patients which leads to better condition of them. 

Reference

1-  The Canon in Medicine. H. Avicenna

几种眼科疾病的蜂毒治疗

B. Kaviani Vahid （伊朗）

（Darou Plasma Iranian (PJV)，Iran）

目前，在蜂疗师中十分流行利用蜂毒治疗某些自身免疫性疾病。源于蜂箱的产品特别是蜂毒在天然毒

素中占有突出的地位。过去几十年，自然疗法越来越受欢迎。原因有很多，其中之一是市场上的普通药物 都存在严重的副作用，其它的原因本文将通过5 个病例治疗报告进行阐述。关键词：蜂毒；眼科疾病；葡萄膜炎；多发性硬化症（MS）；IgG4；自体免疫疾病