Toxicol Ind Health, April 2013 vol. 29 no. 3 264-271
Cigarette smoking is associated with sexual dysfunction and
impaired fertility in males. The aim of this study was to determine the
potential protective effect of honey against the toxic effect of cigarette
smoke (CS) on sexual behavior and fertility of male rats.
Thirty-two adult Sprague-Dawley rats were randomly divided
into four groups (8 rats/group) as control, honey (H), CS and H plus CS (H +
CS) groups. Rats in control and CS groups received oral administration of
distilled water daily while rats in H and H + CS groups received honey (1.2
g/kg body weight/day) by oral gavage. Rats in CS and H + CS groups were also
exposed to CS for 8 min 3 times/day. From 10 to 13 weeks of treatment, each
male rat was cohabited with 3 untreated female rats for sexual behavioral and
reproductive performance studies.
Honey significantly increased the percentages of rats
achieving intromission and ejaculation as well as increased mating and
fertility indexes of male rats exposed to CS. Thus, honey has a protective
effect against CS-induced impaired sexual behavior and fertility in male rats.
No comments:
Post a Comment