Hematostimulative Action of Water - Soluble Derivative of Propolis (WSDP)
Oršolić N, Tadić Z, Benković V, Horvat Knežević A, Ličić D, Đikić D, Bašić I.Department of Animal Physiology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10 000 Zagreb, Croatia
Presented at: 5th German Apitherapy Congress, March 23-25, 2007, Passau, Germany
Summary: We have investigated the effect of a water - soluble derivative of propolis (WSDP) on hematopoiesis of CBA mice using exogenous spleen colony assay (CFUs assay). Given perorally (p.o.) 50 mg/kg to mice for 20 consecutive days WSDP increased the number of exogenous C.F.U.s as compared to control. WSDP given either for 20 or 40 days elevated the number of cells in hematopoietic tissue and increased the number of leucocytes in peripheral blood; prolonged treatment with WSDP also elevated histological appearance of myeloid and megakaryocytic types of C.F.U.s. These studies encourage further investigations on the mode of the radioprotective action of WSDP and its use not only in research concerning hematopoiesis, but also in studies related to its use in combined therapy with radiation and/or cytotoxic drugs.
Saturday, March 31, 2007
Friday, March 30, 2007
Apitherapy May Help Patients with Chronic Hepatitis
Serum Transaminases Decrease in Chronic Hepatitis C Patients by Moroccan Euphorbia Resinifera PropolisPresented at: 5th German Apitherapy Congress, March 23-25, 2007, Passau, Germany
Pr. Faid Mohamed
Hassan II Institute of Agronomy and Veterinary Medicine
PO Box 6202 Rabat-Institute, Morocco
E-mail: faidmohamed@yahoo.fr
Abstract: Chronic hepatitis C often causes significant morbidity in subjects via fatigue and impaired quality of life. In previous studies, propolis extracts and other bee products such as royal jelly have shown to have a protective effect on hepatocytes in vitro as well as in vivo. This effect has been attributed to the antioxidant and free radical scavenging properties of propolis. However, limited information is available on its efficacy in improving liver chemistries and symptoms.
Interferon therapy, which is the only known way to decrease the virus copy and transaminases in the serum, would not really ensure a safe state years after the treatment. Thus, the present investigation was carried out to determine the long-term effect of the oil extract of Moroccan propolis from Euphorbia resinefera (an endemic plant in Morocco) on hepatitis C virus elimination in patients treated during the acute phase of viral hepatitis C…
Activities of the serum glutamate-pyruvate transaminase (SGPT) and the serum glutamate oxaloacetate transaminase (SGOT) were analysed before, during and after 10 months of the beginning of the treatment. Propolis oil extract was administrated orally three times in dose of 70 mg/kg BW, mixed with one tablespoon of multifloral honey one hour before the meal.
Results showed a significant decrease in SGPT and SGOP, as well as a significant inhibition of fatigue symptoms in all patients including those who had been resistant to the conventional therapy. Besides some digestive troubles observed in five patients during the first days of POE intake, no adverse events were occurred, and the POE was safe and well tolerated in all subjects.
These studies suggest that POE along with other adjuvant methods which could enhance the efficiency of bee products, have an improving effect on hepatic dysfunction, and may also confirm the beneficial effect of apitherapy in patients with chronic hepatitis, but this promising effect on virus C clearance should be confirmed in a randomized, double blinded, placebo-controlled study involving more patients.
Thursday, March 29, 2007
UV Sterilization Does Not Change Antibacterial Activity of Honey
Evaluation of the Shelf-Life of Canadian Active HoneysKatrina Brudzynski and Jennie Kim
Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada, L2S 3A1
Abstract presented at: 5th German Apitherapy Congress, March 23-25, 2007, Passau, Germany
Honey is well recognized for its nutritional values, but honey’s proven antibacterial activity creates a basis for its medical use. The objective of this project was to establish a shelf-life of Canadian honey possessing antibacterial activity.
The antibacterial activities were analysed using a broth microdilution assay against two bacterial spp.: Gram-negative Escherichia coli (ATCC14948) and Gram-positive Bacillus subtilis (ATCC 6633).
Since antibacterial activity of Canadian honey depends on the concentration of hydrogen peroxide produced by honey, the levels of this compound were analyzed using peroxide/peroxidase assay in the parallel experiments.
The shelf-life of active honey was assessed by comparison of antibacterial activity during storage of honey (diluted 1:1 with sterile water) for 3 days in room temperature in a sterile environment. The storage reduced both antibacterial activity of honey and production of hydrogen peroxide.
In addition, storage of 50% honey solution encouraged the growth of osmophilic microbes naturally contaminating honey (bacteria, yeast, and moulds) as demonstrated by the standard plate count.
Introduction of sterilization of honey using a germicidal UV lamp prolonged its shelf-life beyond 13 days (further periods were not tested). More importantly, UV sterilization did not change antibacterial activity of honeys nor hydrogen peroxide production levels. In conclusion, honey possessing antibacterial activity and destined for therapeutic use must be sterilized. Moreover, UV irradiation of honey did not diminish either its antibacterial activity or the levels of hydrogen peroxide.
New Energy Bar Contains Royal Jelly, Honey
Recipe for a Boost: Local Entrepreneur Strikes AgainBy Richard Foster, Style Weekly (USA), 3/28/2007
Susan Hardwicke knew she was onto something when she went for a run and felt like she’d “been shot out of a cannon.”
Hardwicke, a local psychologist, entrepreneur and Internet pioneer, achieved local fame in the 1990s for her successful startup, the online educational-testing company EduTest. But soon she might be better known to weightlifters and athletes.
About a year ago, Hardwicke whipped up the formula for a new energy bar in the kitchen of her Wyndham home and sampled it before taking that aforementioned run. Now her Henrico County-based company, Virginia Bionutrients, is selling the Fuser Energy Micro-Bar in four flavors in Vitamin Shoppe stores and gyms nationwide. ..
Hardwicke’s been treating attention-deficit disorders in children and adults for years, and she was working on a formula in her kitchen for naturally treating ADD. That’s when she says she discovered the energetic benefits that resulted in combining ribonucleic acid (RNA) with cocoa, lecithin and natural bee products such as royal jelly and honey.
“Any one of those might give you a little bit of a boost,” Hardwicke says, “but when you put them together as a whole, it’s more than the sum of its parts”…
Wednesday, March 28, 2007
Brazilian Red Propolis: Botanical Origin and Physiological Activities
Presented at: 5th German Apitherapy Congress, March 23-25, 2007, Passau, GermanyBrazilian red propolis is found in the northeast of Brazil inside the mangrove swamps. The Africanized honeybee uses the red propolis to seal off holes and cracks and protects the swarm from pathogenic bacteria and fungi.
Prof. Dr. Yong Kun Park, from UNICAMP University defined 12 different groups of Brazilian propolis. Red propolis was recently classified as group 13 with the botanical origin Dalbergia ecastophyllum (Leguminosae). The botanical origin was verified by observation and different chromatographic methods/histological exams.
Propolis of group 13 is rich in flavonoids and other phenolic compounds with highly interesting physiological properties. Prof. Park´s research group identified the flavonoids liquiritigenin, isoliquiritigenin, daidzein, dalbergin, formononetin and biochanin A. Isoliquritigenin and liquiritigenin inhibited the growth of prostate cancer in vitro.
It also inhibited the enzyme xanthine oxidase. Xanthine oxidase inhibitors were suggested in the treatment of hepatitis and cerebral tumors, as these diseases are augmenting the levels of xanthine oxidase in the serum.
Isoliquiritigenin and liquiritigenin demonstrated also an anti-allergic activity, which was dose-dependant. Formononetin and biochanin A are isoflavonoids with estrogen and anti-fungal activity. They are metabolized to daidzein and genistein, respectively, which are well-known isoflavonoid aglycons found e.g. in soy and are largely used to treat women with problems related to menopause. They showed activity against prostate cancer and breast cancer.
Red propolis had shown analgesic effects in vivo, in concentrations of 25–40 mg dry extract/kg body mass. It has also shown high free radical scavenging and hepato-protective activity.
Dr. Andreas DAUGSCH, Prof. Dr. Yong Kun PARK
State University of Campinas (UNICAMP),
College of Food Engineering,
Department of Food Science,
Laboratory of Food Biochemistry,
Campinas-SP., CEP: 13081-970, Brazil.
E-mail: andreas@daugsch.com
Tuesday, March 27, 2007
Austrian Spa Uses ‘Bee Air’ to Treat Respiratory Problems
Presented at: 5th German Apitherapy Congress, March 23-25, 2007, Passau, Germany
An Austrian spa, called “Tiroler Bienen Welt,” offers treatment with “Bienenluft” or “Bee Air.” Visitors to the spa are given one-hour treatments twice a day for 12 days. They breath air containing volatile compounds released by nectar, honey, pollen, royal jelly, and propolis in the hive and exhale so that their breath does not impact the bees in any way. Spa owners claim success in treating ailments such as asthma. The treatment is only offered May through August.
The spa also offers other apitherapy-related products.
Free translation offered at: http://www.google.com/language_tools
An Austrian spa, called “Tiroler Bienen Welt,” offers treatment with “Bienenluft” or “Bee Air.” Visitors to the spa are given one-hour treatments twice a day for 12 days. They breath air containing volatile compounds released by nectar, honey, pollen, royal jelly, and propolis in the hive and exhale so that their breath does not impact the bees in any way. Spa owners claim success in treating ailments such as asthma. The treatment is only offered May through August.
The spa also offers other apitherapy-related products.
Free translation offered at: http://www.google.com/language_tools
Sunday, March 25, 2007
U.S. Congress Asked to Probe Farming Practices as Cause of Bee Die-Off
Apitherapists issue ‘Passau Declaration’ on Honey Bee Colony Collapse Disorder
(Passau, Germany, 3/25/2007) – An international group of researchers and practitioners of Apitherapy, the medicinal use of bee hive products, meeting in Germany today called on the U.S. Congress to investigate new farming practices as a possible cause of Colony Collapse Disorder (CCD).
CCD, which results in a massive die-off of honey bees, was initially limited to hives in North America, but beekeepers in several European nations have recently reported a similar phenomenon. The cause or causes of CCD have not been determined. Experts say causes of CCD may include environmental stress, malnutrition, unknown diseases, parasitic mites, misuse of pesticides, or pollen and nectar collected by the bees from genetically modified (GM) crops that produce Bacillus thuringiensis (Bt). The problem could affect a third of the foods farmers produce and may have a severe economic impact.
See: Are GM Crops Killing Bees? (Spiegel Magazine)
See: Bee Shortage Could Sting Food Production (Fayetteville Observer)
On March 29, the Horticulture and Organic Agriculture Subcommittee of the House Agriculture Committee will hold a hearing called "Review of Colony Collapse Disorder in Honey Bee Colonies Across the United States."
The “Passau Declaration on Colony Collapse Disorder” was issued today at the conclusion of the 5th International Congress on Bee Products, Apitherapy and Apipuncture in Passau, Germany. It states:
1. We, the scientists, physicians, health practitioners and beekeepers participating in the Fifth International Congress on Bee Products, Apitherapy and Apipuncture,
2. Gathered here in Passau, Germany, in March 2007,
3. Determined to advance the understanding and use of Bee Products, Apitherapy and Apipuncture to promote human health and heal diseases,
4. Acknowledging the important role honeybees play not only in human nutrition and crop pollination, but also in the prevention and treatment of many diseases,
5. Dedicate ourselves unreservedly to the health and well being of the honeybee, the purity of bee products, and the livelihood of the beekeepers, all of which are increasingly threatened all over the world.
We are convinced that:
1. The massive losses of bee colonies in the United States are a warning we should take very seriously,
2. Rapid changes in the earth's climate, ecosystems and agriculture are increasingly adverse to the survival of honeybees,
3. New pesticides and genetically modified plants are being introduced into the environment without sufficient research into their potentially harmful effects on honeybees and the purity of bee products.
4. There is a serious lack of independent research into the environmental impact of new products and farming methods, because far too many of the scientists and regulators in this area have close ties to the chemical and biotech industry.
5. The major losses of honeybees not only threaten our food supply, but also deprive us of many substances, that are of increasing importance to the medical community. As bacteria become more and more resistant to all available antibiotics, hospitals have to be able resorting to bee products, like honey, to control infections.
6. Some of the most promising antiviral substances are found in bee products like Propolis and Royal Jelly. At the same time, bee products are among most effective methods to boost the human immune system. Given the growing danger of a global pandemic with new virus strains like H5N1, the availability of such products in large quantities and high quality will be a key factor in our ability to limit the spread of such a disease.
We are determined to:
1. Inform the public and the decision makers about the medical consequences of the continued decline of the honeybee population.
2. Call attention to agricultural practices that threaten the health of honeybee colonies and the purity of bee products.
We are asking governments to:
1. Fund independent research into the environmental impact of new farming practices, before they are approved for widespread use.
2. Change the approval process for agricultural chemicals and genetically modified crops to require long term studies that also take into account sub-lethal effects on honeybees.
3. Tighten the rules to avoid conflicts of interest in the research and regulatory community, when it comes to assessing the risks associated with new products and methods.
4. Provide funding for research and training in sustainable farming and beekeeping methods.
Contact: Walter Haefeker, member of the board of directors of the German Beekeepers Association, (Haefeker is also vice president of the European Professional Beekeepers Association.), walter@haefeker.de; Dr. Stefan Stangaciu, E-Mail: DrStangaciu@apitherapie.de or drstangaciu@gmail.com (www.Apitherapie.de)
(Passau, Germany, 3/25/2007) – An international group of researchers and practitioners of Apitherapy, the medicinal use of bee hive products, meeting in Germany today called on the U.S. Congress to investigate new farming practices as a possible cause of Colony Collapse Disorder (CCD).
CCD, which results in a massive die-off of honey bees, was initially limited to hives in North America, but beekeepers in several European nations have recently reported a similar phenomenon. The cause or causes of CCD have not been determined. Experts say causes of CCD may include environmental stress, malnutrition, unknown diseases, parasitic mites, misuse of pesticides, or pollen and nectar collected by the bees from genetically modified (GM) crops that produce Bacillus thuringiensis (Bt). The problem could affect a third of the foods farmers produce and may have a severe economic impact.
See: Are GM Crops Killing Bees? (Spiegel Magazine)
See: Bee Shortage Could Sting Food Production (Fayetteville Observer)
On March 29, the Horticulture and Organic Agriculture Subcommittee of the House Agriculture Committee will hold a hearing called "Review of Colony Collapse Disorder in Honey Bee Colonies Across the United States."
The “Passau Declaration on Colony Collapse Disorder” was issued today at the conclusion of the 5th International Congress on Bee Products, Apitherapy and Apipuncture in Passau, Germany. It states:
1. We, the scientists, physicians, health practitioners and beekeepers participating in the Fifth International Congress on Bee Products, Apitherapy and Apipuncture,
2. Gathered here in Passau, Germany, in March 2007,
3. Determined to advance the understanding and use of Bee Products, Apitherapy and Apipuncture to promote human health and heal diseases,
4. Acknowledging the important role honeybees play not only in human nutrition and crop pollination, but also in the prevention and treatment of many diseases,
5. Dedicate ourselves unreservedly to the health and well being of the honeybee, the purity of bee products, and the livelihood of the beekeepers, all of which are increasingly threatened all over the world.
We are convinced that:
1. The massive losses of bee colonies in the United States are a warning we should take very seriously,
2. Rapid changes in the earth's climate, ecosystems and agriculture are increasingly adverse to the survival of honeybees,
3. New pesticides and genetically modified plants are being introduced into the environment without sufficient research into their potentially harmful effects on honeybees and the purity of bee products.
4. There is a serious lack of independent research into the environmental impact of new products and farming methods, because far too many of the scientists and regulators in this area have close ties to the chemical and biotech industry.
5. The major losses of honeybees not only threaten our food supply, but also deprive us of many substances, that are of increasing importance to the medical community. As bacteria become more and more resistant to all available antibiotics, hospitals have to be able resorting to bee products, like honey, to control infections.
6. Some of the most promising antiviral substances are found in bee products like Propolis and Royal Jelly. At the same time, bee products are among most effective methods to boost the human immune system. Given the growing danger of a global pandemic with new virus strains like H5N1, the availability of such products in large quantities and high quality will be a key factor in our ability to limit the spread of such a disease.
We are determined to:
1. Inform the public and the decision makers about the medical consequences of the continued decline of the honeybee population.
2. Call attention to agricultural practices that threaten the health of honeybee colonies and the purity of bee products.
We are asking governments to:
1. Fund independent research into the environmental impact of new farming practices, before they are approved for widespread use.
2. Change the approval process for agricultural chemicals and genetically modified crops to require long term studies that also take into account sub-lethal effects on honeybees.
3. Tighten the rules to avoid conflicts of interest in the research and regulatory community, when it comes to assessing the risks associated with new products and methods.
4. Provide funding for research and training in sustainable farming and beekeeping methods.
Contact: Walter Haefeker, member of the board of directors of the German Beekeepers Association, (Haefeker is also vice president of the European Professional Beekeepers Association.), walter@haefeker.de; Dr. Stefan Stangaciu, E-Mail: DrStangaciu@apitherapie.de or drstangaciu@gmail.com (www.Apitherapie.de)
German Hospital Treats Wounds Using Honey
Wound Care with Antibacterial Honey (Medihoney™) in Pediatric Hematology-OncologyMr. Kai Santos, Department of Pediatric Hematology and Oncology, Children's Hospital, University of Bonn, Adenauerallee 119, 53113, Bonn, Germany, kai.santos@ukb.uni-bonn.de
Presented at: 5th German Apitherapy Congress, March 23-25, 2007, Passau, Germany
The physiologic process of wound healing is impaired and prolonged in pediatric patients receiving chemotherapy. Due to profound immunosuppression, wound infection can easily spread and act as the source of sepsis. Referring to in vitro studies, which confirmed the antibacterial potency of special honey preparations against typical isolates of nosocomially acquired wound infections (including Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant enterococci) and considering the encouraging reports from other groups, Medihoney has now been used in wound care at the Department of Pediatric Oncology, Children's Hospital, University of Bonn for seven years. Supplemented with clinical data from pediatric oncology patients, this article reviews the scientific background and our promising experience with Medihoney in wound care issues at our institution. To collect and analyze the available experience, we prepare an internet-based data documentation module for pediatric wound care with Medihoney.
Medihoney is a CE certified medicinal product for the specific treatment and care of wounds
Treatment of Wounds: Practical Examples
* Care of wound at entry point of hospital devices: long-term implantation of central vein catheter (port, Broviac), PEG-probe/tube, suprapubic bladder catheter
* Post-surgery treatment of wounds, suture dehiscence (also infected, e.g. with MRSA).
* Ulcers, decubitus ulcers odor
* Bedsores radiation dermatitis
* Burns
* Ulcerating tumor wounds
Activity Mechanism of Medihoney:
* Osmotic (anti-edematous) effect
* Formation of gluconic acid and hydrogen peroxide via the enzyme glucose-oxidase (The continuously-emitted amounts of H2O2 are not tissue-toxic but are bactericidal medicinal honey is still antibacterially active in a 5 % solution (MRSA) in which the glucose oxidase activity has been blocked.)
Clinical Activity:
* Anti-edematous effect: wound cleansing action antibacterial effect: wound sterilization
* Wound surface remains moist
* Accelerated granulation and epithelial growth does not damage granulation tissue and prevents or reduces pain when changing bandages reduces development of offensive wound odors
Materials Used in Conjunction with Medihoney:
* AQUACEL® forms a soft layer of gel when in contact with wound secretions and is able to absorb a large amount of liquid, even under pressure
* Calcium alginate as well as alkali and magnesium salts of alginic acid form a highly viscous gel in the presence of water or wound secretions
Algosteril® - Johnson & Johnson
Curasorb® - Tyco
Kaltostat ® - Convatec
Melgi Sorb ® - Mölnlyke
Sea Sorb Soft ® - Coloplast
Sorbalgon ® - Hartmann
Sorbsan ® - B. Braun
Suprasorb ® A - Lohrmann+Rauscher
Tegagen ® - 3M
Trionic ® - Johnson+Johnson
* Wound border area protection by means of preparations containing silicon, e.g. Cavillon® 3M, is recommended when frequent bandage changes are necessary
* Medihoney should remain on the wound until the next bandage change. Nearly all types of bandages are suitable.
Limitations and Side Effects:
* Formation of a honey crust due to gel remains
* Pain after application (high pH) especially with ulcus cruris (ca. 5 %)
* Local reactions (ca. 2 %), local eczema caused by Medihoney™
* Cost (80 Euros per 5-pack of Medihoney)
Saturday, March 24, 2007
Studies: Bee Venom Free of Pesticides, Antimicrobial, Stimulates Growth
Our Experience on Bee Venom Evaluations and its Pharmaceutical EfficacyNational Institute of Agricultural Science and Technology
5th German Apitherapy Congress, March 23-25, 2007, Passau, Germany
Paper 1 - Determination of residual pesticides in collected bee venom using bee venom collector
Abstract: This study was carried out to determine the 151 residual pesticides in 20 bee venom samples collected using bee venom collector from apiary of various sites of Korea through the year from May to September 2005…The 151 kinds of pesticide were not detected in bee venom at all. No one sample was found to approach proposed national maximum residue limits in Korea.
Paper 2 - The minimum inhibitory concentration (MIC) of bee venom against bacteria isolated from pigs and chickens
Abstract: Bee venom has been shown to exhibit antimicrobial activities. Bee venom has been used for the purpose of diseases treatment for human being and other animals including pigs and chickens. We performed tests for antibacterial activities and evaluated minimum inhibitory concentration (MIC) of bee venom against bacteria isolated from pigs and chickens with disease…Multiple drug resistant patterns were found in most strains isolated from pig and chicken. These results suggest that bee venom showed very effective antibacterial activities on pathogenic bacteria in pigs and chickens.
Paper 3 - Effects of honeybee venom injection on the growth performance and hematological characteristics of pigs
Abstract: This study was conducted to evaluate effects of honeybee venom injection (VI) collected using bee venom collector compared to that of bee venom acupuncture (VA) on the body weight gain, growth rate and hematological characteristics of piglets…These results suggested that the treatment of honeybee venom injection collected using bee venom collector could be used effectively for the increase productivity.
Paper 4 - Therapeutic effects of honeybee venom injection on bovine mastitis
Abstract: The therapeutic effective way of honeybee venom collected using bee venom collector on bovine mastitis was investigated. Mastitis cows from four farms were selected in the Yang-pyeong areas…These results suggested that bee venom treatment might be effective for treatment of bovine mastitis.
Paper 5 - Effect of Honey Bee Venom on Microglial Cells Nitric Oxide and Tumor Necrosis Factor Production Stimulated by LPS
Abstract: Abnormal activation of microglial cells has been implicated in various neurodegenerative diseases. Results showed that venom (KBV) produced and purified in Korea regulated lipopolysaccharides (LPS)–induced nitric oxide (NO) and tumor necrosis factor-alpha (TNF) in the murine microglia, BV-2 cell line…
S.M. Han
Applied Sericulture & Apiculture Division, NIAST, 61 Seodun-Dong, Suwon, 441-100, Korea
Phone: 82-31-290-8510
Fax: 82-31-290-8516
E-mail: sangmih@rda.go.kr
Paper 1 - Determination of residual pesticides in collected bee venom using bee venom collector
Abstract: This study was carried out to determine the 151 residual pesticides in 20 bee venom samples collected using bee venom collector from apiary of various sites of Korea through the year from May to September 2005…The 151 kinds of pesticide were not detected in bee venom at all. No one sample was found to approach proposed national maximum residue limits in Korea.
Paper 2 - The minimum inhibitory concentration (MIC) of bee venom against bacteria isolated from pigs and chickens
Abstract: Bee venom has been shown to exhibit antimicrobial activities. Bee venom has been used for the purpose of diseases treatment for human being and other animals including pigs and chickens. We performed tests for antibacterial activities and evaluated minimum inhibitory concentration (MIC) of bee venom against bacteria isolated from pigs and chickens with disease…Multiple drug resistant patterns were found in most strains isolated from pig and chicken. These results suggest that bee venom showed very effective antibacterial activities on pathogenic bacteria in pigs and chickens.
Paper 3 - Effects of honeybee venom injection on the growth performance and hematological characteristics of pigs
Abstract: This study was conducted to evaluate effects of honeybee venom injection (VI) collected using bee venom collector compared to that of bee venom acupuncture (VA) on the body weight gain, growth rate and hematological characteristics of piglets…These results suggested that the treatment of honeybee venom injection collected using bee venom collector could be used effectively for the increase productivity.
Paper 4 - Therapeutic effects of honeybee venom injection on bovine mastitis
Abstract: The therapeutic effective way of honeybee venom collected using bee venom collector on bovine mastitis was investigated. Mastitis cows from four farms were selected in the Yang-pyeong areas…These results suggested that bee venom treatment might be effective for treatment of bovine mastitis.
Paper 5 - Effect of Honey Bee Venom on Microglial Cells Nitric Oxide and Tumor Necrosis Factor Production Stimulated by LPS
Abstract: Abnormal activation of microglial cells has been implicated in various neurodegenerative diseases. Results showed that venom (KBV) produced and purified in Korea regulated lipopolysaccharides (LPS)–induced nitric oxide (NO) and tumor necrosis factor-alpha (TNF) in the murine microglia, BV-2 cell line…
S.M. Han
Applied Sericulture & Apiculture Division, NIAST, 61 Seodun-Dong, Suwon, 441-100, Korea
Phone: 82-31-290-8510
Fax: 82-31-290-8516
E-mail: sangmih@rda.go.kr
Friday, March 23, 2007
Apitherapy News to Report from the 5th German Apitherapy Congress and Expo
Watch for reports about presentations offered at the 5th German Apitherapy Congress and Expo currently underway in Passau, Germany.
Romanian Conference on Apiculture, Apitherapy – May 3-5, 2007
Apiculture – From Science to Agribusiness and Apitherapy
May 3-5, 2007, Cluj-Napoca, Romania
The 1st International Conference on Apiculture - From Science to Agribusiness and Apitherapy - is organized by University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Department of Apiculture and Sericulture
There will also be a summer program on beekeeping and apitherapy.
May 3-5, 2007, Cluj-Napoca, Romania
The 1st International Conference on Apiculture - From Science to Agribusiness and Apitherapy - is organized by University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Department of Apiculture and Sericulture
There will also be a summer program on beekeeping and apitherapy.
Thursday, March 22, 2007
Honey, Olive Oil and Beeswax Effective in Treating Hemorrhoids, Anal Fissures
The Safety and Efficacy of a Mixture of Honey, Olive Oil and Beeswax for the Management of Hemorrhoids and Anal Fissure: A Pilot Study
TSW Holistic Health & Medicine
Abstract: We have found that a mixture of honey, olive oil and beeswax was effective for treatment of diaper dermatitis, psoriasis, eczema and skin fungal infection. The mixture has antibacterial properties. A prospective pilot study was conducted to evaluate therapeutic effect of topical application of the mixture on patients with anal fissure or hemorrhoids…
Honey mixture significantly reduced bleeding and relieved itching in patients with hemorrhoids. Patients with anal fissure showed significant reduction in pain, bleeding and itching after the treatment. No side effect was reported with use of the mixture. We conclude that a mixture of honey, olive oil and beeswax is safe and clinically effective in the treatment of hemorrhoid and anal fissure, which pave the way for further randomized double blind studies.
TSW Holistic Health & Medicine
Abstract: We have found that a mixture of honey, olive oil and beeswax was effective for treatment of diaper dermatitis, psoriasis, eczema and skin fungal infection. The mixture has antibacterial properties. A prospective pilot study was conducted to evaluate therapeutic effect of topical application of the mixture on patients with anal fissure or hemorrhoids…
Honey mixture significantly reduced bleeding and relieved itching in patients with hemorrhoids. Patients with anal fissure showed significant reduction in pain, bleeding and itching after the treatment. No side effect was reported with use of the mixture. We conclude that a mixture of honey, olive oil and beeswax is safe and clinically effective in the treatment of hemorrhoid and anal fissure, which pave the way for further randomized double blind studies.
Honey Decreased Prostaglandins Level in AIDS Patient
Influence of Natural Honey on Biochemical and Hematological Variables in AIDS: A Case Study
The Scientific World Journal
Abstract: Honey lowers prostaglandins and elevates nitric oxide (NO) in various biological fluids in normal persons. NO and prostaglandin play a role in pathogenesis of AIDS. The study was designed to assess the effect of natural honey on prostaglandins and NO levels, blood indices and biochemical tests in a 40 year-old woman with AIDS. ..
Results showed that prostaglandins level compared with normal subjects were elevated in patient with AIDS. Natural honey decreased prostaglandins levels, and elevated NO-end product, percentage of lymphocytes, platelet count, and serum protein, albumin and copper levels. It might be concluded that natural honey decreased prostaglandins level, elevated NO production and improved hematological and biochemical tests in a patient with a long history of AIDS.
The Scientific World Journal
Abstract: Honey lowers prostaglandins and elevates nitric oxide (NO) in various biological fluids in normal persons. NO and prostaglandin play a role in pathogenesis of AIDS. The study was designed to assess the effect of natural honey on prostaglandins and NO levels, blood indices and biochemical tests in a 40 year-old woman with AIDS. ..
Results showed that prostaglandins level compared with normal subjects were elevated in patient with AIDS. Natural honey decreased prostaglandins levels, and elevated NO-end product, percentage of lymphocytes, platelet count, and serum protein, albumin and copper levels. It might be concluded that natural honey decreased prostaglandins level, elevated NO production and improved hematological and biochemical tests in a patient with a long history of AIDS.
Wednesday, March 21, 2007
Brazilian Green Propolis Displays Good Anti-Ulcer Activity
Effect of Brazilian Green Propolis on Experimental Gastric Ulcers in RatsJournal of Ethnopharmacology, 2007 Apr 4;110(3):567-71. Epub 2006 Oct 28
Propolis is a resinous hive product collected by honeybees from plants. The propolis produced in Southeastern of Brazil is known as green propolis because of its color. Modern herbalists recommend its use because it displays antibacterial, antifungal, antiviral, hepatoprotective, anti-inflammatory, immunomodulatory and anti-ulcer properties. The anti-ulcer activity of green propolis hydroalcoholic crude extract was evaluated by using models of acute gastric lesions induced by ethanol, indomethacin and stress in rats…
Animals pretreated with propolis hydroalcoholic crude extract (50, 250 and 500mg/kg) showed a significant reduction in lesion index, total affected area and percentage of lesion in comparison with control group (p<0.05) in the ethanol-induced ulcer model. Green propolis extract, at a higher dose (500mg/kg), displayed a significant protection by reducing (p<0.05) the evaluated parameters in the gastric ulceration induced by indomethacin…
These findings indicate that Brazilian green propolis displays good anti-ulcer activity, corroborating the folk use of propolis preparations, and contributing for its pharmacological validation.
Tuesday, March 20, 2007
Study: Honey More Effective Against Bacteria Than Antibiotics
Antimicrobial Activity and Pollen Composition of Honey Samples Collected from Different Provinces in Turkey
Natural Product Research, 2007 Mar;21(3):187-95
The antibacterial activity of honey samples from different sources were collected and investigated against Bacillus cereus, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 27736, Morganella morganii, Micrococcus luteus NRRL B-4375, Escherichia coli ATCC 35218, and Candida albicans…
The results showed that majority of the honey samples (75%) generally inhibitied the bacteria tested…
The honey proved more effective on bacteria than antibiotics.
Natural Product Research, 2007 Mar;21(3):187-95
The antibacterial activity of honey samples from different sources were collected and investigated against Bacillus cereus, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 27736, Morganella morganii, Micrococcus luteus NRRL B-4375, Escherichia coli ATCC 35218, and Candida albicans…
The results showed that majority of the honey samples (75%) generally inhibitied the bacteria tested…
The honey proved more effective on bacteria than antibiotics.
Beeswax Product Saves Dry Skin
Joe Graedon and Teresa Graedon, Atlanta Journal (USA), 3/20/2007Q: I just had to put in my two cents on dry, cracked hands. My father and I used to compare how many bandages we would be wearing each week because our hands were in such bad shape. I finally found something that worked: Surgeon's Skin Secret. It contains beeswax, lanolin and mineral oil. It lasts a long time. I have had my jar for three years. Since beehives have been found that are 100 years old, I don't worry about it going rancid.
Please let your readers know about this product. Working in the post office as I do, my skin dries out even more from the paper. This is great for mail carriers!
A: We found Surgeon's Skin Secret on the Web at www.jamarklabs.com. According to the manufacturer, it was developed by a plastic surgeon in 1950. Some people are allergic to lanolin, so caution is appropriate. This moisturizer is not inexpensive (about $29 for 16 ounces)...
Monday, March 19, 2007
Apitherapy News Adds New ‘Apitherapy and Beekeeping’ Section
(March 19, 2007) – Apitherapy News, the Internet's best source of information about the medicinal use of bee products, today added a new subject area called “Apitherapy and Beekeeping.”
The new area of the Apitherapy News website will focus on news items in which the art and science of beekeeping overlaps with Apitherapy.
Today’s news item features a letter to the editor critical of the possible use of textured vegetable protein (TVG) in pollen substitutes fed to honey bee.
The new area of the Apitherapy News website will focus on news items in which the art and science of beekeeping overlaps with Apitherapy.
Today’s news item features a letter to the editor critical of the possible use of textured vegetable protein (TVG) in pollen substitutes fed to honey bee.
Writer Questions Use of Soy Protein in Pollen Substitutes
Bees Getting the Wrong FoodChico Enterprise-Record (USA), 3/19/2007
I was very surprised to read that beekeepers feed their bees soy protein bricks mixed with pollen and honey. The soy protein brick is most likely a toxic mix containing "textured vegetable protein" (TVG). TVG is a manufactured, unnatural food. Soybeans are routinely treated with high heat, oxidizing agents, organic solvents, alkalis and acids to improve flavor, color and texture. This deactivates the natural anti-nutritional factors in soy and allows preparation of concentrated soy protein products like TVG and others. Most of the foods in the American supermarket contain these chemicals and unfortunately they are a large part of our children's diets in chicken nuggets, fast food hamburgers, spaghetti sauces, and baked goods contained in school lunches.
Traditionally, soy was eaten in small quantities along with small amounts of meats, eggs, and other proteins. Now, factory farms are displacing the rain forest in the Amazon to "feed the world" soy that is modified, textured, hydrogenated and more. Most soybeans grown in the world are also genetically modified organisms (GMOs). GMO corn is known to negatively affect butterflies, so what about GMO soy? Add to this the tons of pesticides and herbicides used to grow this mega food and you have a food not worth eating.
Read "The Whole Soy Story" by Kaayla Daniel and "The Omnivores Dilemma" by Michael Pollan. What you may realize is that TVGs, trans fats, high fructose corn syrup, GMOs and other factory foods are deadly to us, and our friends the birds and the bees.
Trish Puterbaugh, Cohasset
Sunday, March 18, 2007
Bee Venom Therapy Popular in Indonesia
Honey Bees and Alternative MedicationBy P.J. Leo, The Jakarta Post (Indonesia), 3/18/2007
Practiced for the first time in China and later in Egypt centuries ago, bee acupuncture today exists in cities across Indonesia.
Bee acupuncture, or the use of bee stings in medication, has developed rapidly and is already a popular alternative healing method.
The Bee Center in Cibubur, East Jakarta, is one of the places that provides this alternative healing, known as apitherapy. Not only does the center breed bees for honey and pollen; it also offers medication using bee stings…
Saturday, March 17, 2007
Bee Venom Component Induces Tumor Cell Death, Stimulates Immune System
Bee Venom Secretory Phospholipase A2 and Phosphatidylinositol-Homologues Cooperatively Disrupt Membrane Integrity, Abrogate Signal Transduction and Inhibit Proliferation of Renal Cancer Cells
Cancer Immunology, Immunotherapy, 2007 May;56(5):627-40. Epub 2006 Sep 1
Bee venom secretory phospholipase A2 (bv-sPLA2) and phosphatidylinositol-(3,4)-bisphosphate (PtdIns(3,4)P2) act synergistically to induce cell death in tumour cells of various origins with concomitant stimulation of the immune system…
In conclusion, we suggest that the cytotoxic activity mediated by PtdIns(3,4)P2 and bv-sPLA2 is due to cell death that results from disruption of membrane integrity, abrogation of signal transduction and the generation of cytotoxic lyso-PtdIns(3,4)P2.
Cancer Immunology, Immunotherapy, 2007 May;56(5):627-40. Epub 2006 Sep 1
Bee venom secretory phospholipase A2 (bv-sPLA2) and phosphatidylinositol-(3,4)-bisphosphate (PtdIns(3,4)P2) act synergistically to induce cell death in tumour cells of various origins with concomitant stimulation of the immune system…
In conclusion, we suggest that the cytotoxic activity mediated by PtdIns(3,4)P2 and bv-sPLA2 is due to cell death that results from disruption of membrane integrity, abrogation of signal transduction and the generation of cytotoxic lyso-PtdIns(3,4)P2.
Friday, March 16, 2007
Medicinal Honey Blend Used in New Body-Care Line
Body Care Goes Organic with a Sweet ApproachBy Elaine Walker, The Miami Herald (USA), 3/15/2007
''The natural foods skin-care industry has to really clean up its act,'' Julie Gerber said.
That realization launched the Gerbers on a new mission and the creation of BeeCeuticals Organics, a project more than three years in the making.
The Fort Lauderdale company's line of nine body-care products includes creams and shampoo, ranging in price from $9.95 to $22.95. BeeCeuticals products feature organic ingredients, without many of the chemicals, synthetic fragrances and preservatives found in other products. They don't use sodium laureth sulfate, parabens or hydrosols.
Instead, everything is made with a 100 percent organic honey blend, featuring medicinal honeys that have been used for centuries to heal the skin. Plus, a percentage of company profits go back to help save the bees, whose numbers are declining worldwide.
Richie Gerber proudly shows off the quality of his raw ingredients, which he sources from as far away as New Zealand and Africa. The BeeCeuticals honey is a dark cloudy liquid that is unfiltered and nonirradiated, compared to the white powderized honey Gerber claims many companies use or the clear golden yellow honey found in the supermarket.
It was the Gerbers' partner Jon Guerra, a Fort Lauderdale chemist, who turned them on to the benefits of medicinal honey based on his own experiences with a wound that didn't respond to traditional medicine…
Meanwhile, the BeeCeuticals line is already drawing positive reviews from customers. The line is available on the Web at www.healthfromthehive.com and in a few dozen locations in Florida and elsewhere. Whole Foods just started introducing it in its Florida stores and it's featured in several Broward County health foods stores.
The medicinal benefits of the BeeCeuticals products are what has impressed Marc Leach, pharmacist and owner of the Las Olas Chemist. Leach was one of the first to start selling the products about six months ago. He regularly recommends the Bee-yond Body Balm for use by diabetics on their feet and the Honey Thyme Hand and Body Lotion for people suffering from psoriasis or eczema.
''I've found this to be the most effective of anything I've tried in the past,'' Leach said. ``It's amazing to me that organic honey could have that effect.''
Thursday, March 15, 2007
Arabic Website Focused on Bee Venom Therapy
مركز بحوث العلاج بسم النحل
Bee Venom Therapy Research Center (Egypt)
The Bee Venom Therapy Research Center site is in Arabic. To translate the site into English, go to: http://www.google.com/language_tools
Bee Venom Therapy Research Center (Egypt)
The Bee Venom Therapy Research Center site is in Arabic. To translate the site into English, go to: http://www.google.com/language_tools
Wednesday, March 14, 2007
Upcoming Apitherapy Events in the United States
Missouri Beekeeping Conference to Feature Apitherapy Workshop
Missouri Beekeepers to Host Conference
Jefferson City News Tribune (USA), 3/11/2007
The Missouri State Beekeepers Association is hosting a state conference on Friday and Saturday in Jefferson City.
The group will tour the Capitol and Governor's Mansion. Topics for the conference include: Beekeeping 101, Allergic Reactions to Insect Stings, and Using Beeswax in Lotions and Creams.
There will also be an apitherapy workshop which is open to the public at 1 p.m., Saturday at the Capitol Plaza. Apitherapy is the ancient cure that involves treating disorders with the help of bee venom. Featured speaker is Reyah Carlson, secretary of the American Apitheraphy Society.
New York: Bee Venom Therapy
Westchester.com, 3/13/2007
Wednesday, March 20, 10-11:30 a.m., The Main House, Bldg. A
Beekeeper Tom Cohn of Hilltop Hanover Farm Honey Inc. will present an educational program on the medicinal properties of the honey bee. The program will include a lecture and demonstration by Alan Lorenzo, a bee venom therapist, titled “The Healing Honey Bee: the Buzz on Bee Venom Therapy.” Seating is limited, so reservations are recommended. Call (914) 962-2368.
North Carolina: Charles Mraz Apitherapy Course and Conference
April 26-29, 2007
Research Triangle Park, North Carolina (USA)
Missouri Beekeepers to Host Conference
Jefferson City News Tribune (USA), 3/11/2007
The Missouri State Beekeepers Association is hosting a state conference on Friday and Saturday in Jefferson City.
The group will tour the Capitol and Governor's Mansion. Topics for the conference include: Beekeeping 101, Allergic Reactions to Insect Stings, and Using Beeswax in Lotions and Creams.
There will also be an apitherapy workshop which is open to the public at 1 p.m., Saturday at the Capitol Plaza. Apitherapy is the ancient cure that involves treating disorders with the help of bee venom. Featured speaker is Reyah Carlson, secretary of the American Apitheraphy Society.
New York: Bee Venom Therapy
Westchester.com, 3/13/2007
Wednesday, March 20, 10-11:30 a.m., The Main House, Bldg. A
Beekeeper Tom Cohn of Hilltop Hanover Farm Honey Inc. will present an educational program on the medicinal properties of the honey bee. The program will include a lecture and demonstration by Alan Lorenzo, a bee venom therapist, titled “The Healing Honey Bee: the Buzz on Bee Venom Therapy.” Seating is limited, so reservations are recommended. Call (914) 962-2368.
North Carolina: Charles Mraz Apitherapy Course and Conference
April 26-29, 2007
Research Triangle Park, North Carolina (USA)
Tuesday, March 13, 2007
Propolis Component Reduced Number of Newly-Formed Blood Vessels to Tumors
Suppression of Tumor-Induced Angiogenesis by Brazilian Propolis
Cancer Letters, 2007 Mar 5
Propolis, a resinous substance collected by honeybees from various plant sources, possesses various physiological activities such as antitumor effects. We have previously shown that propolis of Brazilian origin was composed mainly of artepillin C and that its constituents were quite different from those of propolis of European origin. In this report, we examined an antiangiogenic effects of Brazilian propolis and investigated whether artepillin C was responsible for such effects.
In an in vivo angiogenesis assay using ICR mice, we found that the ethanol extract of Brazilian propolis (EEBP) significantly reduced the number of newly formed vessels…
Judging from its antiangiogenic activity in vitro and in vivo, we concluded that artepillin C at least in part is responsible for the antiangiogenic activity of EEBP in vivo. Artepillin C may prove useful in the development of agents and foods with therapeutic or preventive activity against tumor angiogenesis.
Cancer Letters, 2007 Mar 5
Propolis, a resinous substance collected by honeybees from various plant sources, possesses various physiological activities such as antitumor effects. We have previously shown that propolis of Brazilian origin was composed mainly of artepillin C and that its constituents were quite different from those of propolis of European origin. In this report, we examined an antiangiogenic effects of Brazilian propolis and investigated whether artepillin C was responsible for such effects.
In an in vivo angiogenesis assay using ICR mice, we found that the ethanol extract of Brazilian propolis (EEBP) significantly reduced the number of newly formed vessels…
Judging from its antiangiogenic activity in vitro and in vivo, we concluded that artepillin C at least in part is responsible for the antiangiogenic activity of EEBP in vivo. Artepillin C may prove useful in the development of agents and foods with therapeutic or preventive activity against tumor angiogenesis.
Monday, March 12, 2007
Comvita Reduces the Price of Honey Wound Dressings
Manuka Honey Dressings Now More Affordable in UKPR Web, 3/12/2007
(PRWEB) March 12, 2007 -- The world's leading active manuka honey brand from New Zealand, Comvita, had previously introduced their innovative Apinate dressings. These are a superior wound dressing ready impregnated with active manuka honey, with all of its natural antiseptic and healing properties. It uses a calcium aginate dressing, which is derived from seaweed, being biodegradable, and ensuring that any fibres trapped in a wound a readily biodegraded…
At $44.95 for a pack of three dressings, they had been too expensive an option for many people who would benefit from them.
Recognising this, in an effort to make them more affordable to a greater range of people Comvita have now made a significant reduction in their price. With a new RRP of £29.95, a third lower than before, a greater number of people will be able to benefit from these innovative dressings.
For those for whom it is still too expensive, we recommend using the Manukacare 18+ (a tube of the manuka honey) together with their own source of dressings. The aim is to allow as many people as possible the opportunity to naturally help their wound healing...
Sunday, March 11, 2007
Propolis has Amoebicidal, Cysticidal, Properties
In Vitro Amoebicidal Activity of Propolis on Acanthamoeba CastellaniiJournal of Ocular Pharmacology and Therapeutics, 2007 Feb;23(1):40-5
Purpose: The aim of this study was to investigate the in vitro effects of an ethanolic extract of propolis on the growth and adherence of Acanthamoeba castellanii trophozoites and cysts…
Results: After 1-72 h, incubation in concentrations between 2.0 and 6.0 mg/mL, its effect was amoebistatic; at concentrations of 8.0 mg/mL and higher, its effect was amoebicidal. After 48 h or longer incubation times at 15.62 mg/mL and at higher concentrations, the propolis extract was cysticidal…
Conclusions: These findings indicate that ethanolic extract of propolis has amoebicidal, as well as cysticidal, properties for Acanthamoeba trophozoites and cysts. Propolis alone, or in combination with other amoebicidal agents, may be used in clinical practice after further investigations.
Saturday, March 10, 2007
Puerto Rico Beekeeping Conference to Discuss Apitherapy
1er Congreso Antillano de ApiculturaDel 28 de junio al 1ro de julio de 2007
Pichis Convention Center Guayanilla, Puerto Rico
Temática principal: La diversificación de la producción apícola; La Apiterapia; Enfermedades de abejas y tratamientos; Determinación del origen floral de las mieles; Flora Melífera y Polinización.
Conferenciantes:
Dr. Moises Asis (EE.UU.)
Dr. Vetaley Stashenko (EE.UU)
Dr. Pedro Rodríguez (EE.UU./España/Puerto Rico)
Sra. Trinidad Terrazas (Mexico)
Ing. Cecilia Inés Sánchez (Argentina/Puerto Rico)
Ing. Daniel Pérez Moro (Puerto Rico)
Además de ser un Congreso también tendremos un EXPO.
Visite el website oficial del evento: http://www.mielesdepuertorico.com para información detallada.
Translate
Friday, March 09, 2007
Newspaper Profiles Canadian Apitherapist
A Beehive of ActivityBy Katrina Simmons, The Hamilton Spectator (Canada), 3/8/2007
Honey has been around since the beginning of time. The pharoahs of Egypt were buried with honey, says beekeeper and apitherapist Annie vanAlten of Dutchman's Gold honey and maple products, and this powerhouse of nutrition is even mentioned numerous times in the Bible…
In recent years, vanAlten has turned her attention to the health benefits of other products of the hive, and added Annie's Apitherapy to the Dutchman's Gold label. She started attending international workshops and congresses to learn and lecture about the therapeutic use of bee products (apitherapy).
"Royal jelly is B-complex and a pick-me-upper," she instructs. "Propolis is a natural antibiotic, and bee pollen boosts the immune system, is an energy booster and a multivitamin." Even honey itself is an anti-bacterial, she says, that can be used as a wound dressing.
All of these products, plus beeswax candles, wax gift boxes, soothing skin creams, soaps and salves crowd the shelves of the Dutchman's Gold shop in Carlisle, alongside the jars of honey. VanAlten does her best to educate everyone who walks through the door about the amazing and age-old world of bees.
Dutchman's Gold is at 300 Carlisle Road in Carlisle (905-689-6371/ www.dutchmansgold.com or www.anniesapitherapy.com). You can also find their honey in food stores throughout Ontario.
Thursday, March 08, 2007
Wednesday, March 07, 2007
Propolis a 'Useful Adjunctive Agent' for Treatment of Keratitis
Keratitis Therapy
Researchers from Mustafa Kemal University report on findings in keratitis therapy
Drug Week, March 9, 2007
Current study results from the report, "Comparative trial of different anti-bacterial combinations with propolis and ciprofloxacin on Pseudomonas keratitis in rabbits," have been published. "The aim of the current study was to evaluate the effects of five different treatment combinations to find out whether propolis could be an alternative or an adjunctive treatment, in experimental Pseudomonas aeruginosa keratitis. Intrastromal P. aeruginosa strains were given to both eyes of 20 young New Zealand white rabbits. The rabbits were randomly divided equally into five treatment groups; ciprofloxacin and dexamethasone drops (C+D), ciprofloxacin drop (C), ciprofloxacin and propolis drops (C+P), propolis drop (P), 3% ethanol drop (control), respectively," scientists in Antakya, Turkey report.
"Directly before the first treatment and 108 h after inoculation, the eyes were examined by slit lamp to assess the corneal opacity and rabbits were sacrificed for bacterial count. The mean corneal opacity scores and the mean bacterial counts log cfu/ml were significantly different in the treatment groups (p=0.001; ANOVA). According to post hoc tests for both the mean bacterial counts and corneal opacity scores, C+D, C, C+P groups were found to be statistically the same (p >0.05), and although the P group had significantly better scores than the control group it did not reach the scores of the rest of the treatment groups (p <0.01)," wrote Y. Onlen and colleagues, Mustafa Kemal University.
The researchers concluded: "We conclude that propolis may be a useful adjunctive agent but should not be regarded as a replacement for traditional antibiotic therapy for P. aeruginosa keratitis in rabbits."
Researchers from Mustafa Kemal University report on findings in keratitis therapy
Drug Week, March 9, 2007
Current study results from the report, "Comparative trial of different anti-bacterial combinations with propolis and ciprofloxacin on Pseudomonas keratitis in rabbits," have been published. "The aim of the current study was to evaluate the effects of five different treatment combinations to find out whether propolis could be an alternative or an adjunctive treatment, in experimental Pseudomonas aeruginosa keratitis. Intrastromal P. aeruginosa strains were given to both eyes of 20 young New Zealand white rabbits. The rabbits were randomly divided equally into five treatment groups; ciprofloxacin and dexamethasone drops (C+D), ciprofloxacin drop (C), ciprofloxacin and propolis drops (C+P), propolis drop (P), 3% ethanol drop (control), respectively," scientists in Antakya, Turkey report.
"Directly before the first treatment and 108 h after inoculation, the eyes were examined by slit lamp to assess the corneal opacity and rabbits were sacrificed for bacterial count. The mean corneal opacity scores and the mean bacterial counts log cfu/ml were significantly different in the treatment groups (p=0.001; ANOVA). According to post hoc tests for both the mean bacterial counts and corneal opacity scores, C+D, C, C+P groups were found to be statistically the same (p >0.05), and although the P group had significantly better scores than the control group it did not reach the scores of the rest of the treatment groups (p <0.01)," wrote Y. Onlen and colleagues, Mustafa Kemal University.
The researchers concluded: "We conclude that propolis may be a useful adjunctive agent but should not be regarded as a replacement for traditional antibiotic therapy for P. aeruginosa keratitis in rabbits."
Tuesday, March 06, 2007
Veterinarian Uses Bee Venom to Treat Animals
Vet Finds Alternatives in Treating PetsArizona Republic (USA), 3/6/07
Judy Stolz never thought she would be using substances such as bee venom, spiders, tiger lily and marigolds, not to mention sulfur, sodium chloride and arsenic.
To treat animals and people, no less.
No, she isn't a witch doctor. She is one of a growing number of homeopathic/holistic veterinarians who use a combination of conventional and alternative methods of treatment, including acupuncture...
Information: http://www.drstolz.com/
Single-Source Honeys Better Choice for Diabetics
It's a Sweet World
By Natascha Mirosch, The Courier Mail (Australia), 6/6/2007
Australia has more floral sources suitable for making honey than any other country and we have created a particularly strong niche market in single-variety flower honey, that is, honey sourced from bees which feed exclusively on a single type of flower.
The single-flower honeys like ironbark, leatherwood or lavender have found great favour with the honey lover (see box, right). Some single-flower varieties are also lower GI, making them better choices than blends, in controlled amounts, for diabetics…
By Natascha Mirosch, The Courier Mail (Australia), 6/6/2007
Australia has more floral sources suitable for making honey than any other country and we have created a particularly strong niche market in single-variety flower honey, that is, honey sourced from bees which feed exclusively on a single type of flower.
The single-flower honeys like ironbark, leatherwood or lavender have found great favour with the honey lover (see box, right). Some single-flower varieties are also lower GI, making them better choices than blends, in controlled amounts, for diabetics…
Monday, March 05, 2007
New US Companies Use Bee Products for Skin Care
Youths Create Body-Care LineJohn O’Connell, Idaho State Journal (USA), 3/4/2007
CHUBBUCK — When school lets out, the Judd children start mixing and packaging their secret formulas.
The five siblings, ages 7 to 16, have become a business team. They recently started combing the city for vendors to carry their line of homemade skin-care products, which they call IHaveHives. They use only natural ingredients — such as lavender, eucalyptus, beeswax, almond oil, coconut oil and olive oil — in their lip balms, hand creams, body butters and bars. Exact quantities and a few specific ingredients are trade secrets...
Veteran Natural Food Entrepreneurs Launch BeeCeuticals Organics™ Skin and Hair Care Products
PR.com, 3/3/2007
The Gerbers met Jon Guerra, a Cornell University graduate, chemist and herbalist. When Jon was 21 years old, a boating accident caused a wound on his leg that would not heal. His father, a doctor, began using medicinal honey and the wound cleared up immediately. Like the Gerbers, Jon shares a passion for the miraculous products of the hive and the three teamed up, researching and developing their own blend of honeys from around the world which were selected for their proven medicinal properties and those that were most beneficial to the skin, thus creating their own proprietary 100% Organic Holistic Honey Blend ™.
When other skin care lines claim they use honey, most actually use cheap powdered honeys or honey that is heated, filtered, irradiated and pasteurized because they are easier to handle during the manufacturing process.
These cheaper honeys have little or no health benefits. BeeCeuticals Organics ™ uses honey that is certified organic, raw, unfiltered and never heated above hive temperature. Their proprietary Organic Holistic Honey Blend ™ is a potent anti-aging ingredient that benefits the skin due to its antioxidant density and curative factors.
Their product line includes Honey Thyme™ Hand and Body Lotion, Queen Bee for a Day Cream™, Bee Line Free™ Eye Cream, Bee-yond Body Balm™ Skin Care Repair Cream, and Bee-Hair-Now™ Hydrating Honey Shampoo & Conditioner, and all are made with their proprietary holistic honey blend…
Sunday, March 04, 2007
Study Examines Action of Royal Jelly on Cholesterol
Changes in Hepatic Gene Expression Associated with the Hypocholesterolaemic Activity of Royal Jelly
Journal of Pharmacy and Pharmacology, 2006 Dec;58(12):1683-9
Royal jelly (RJ) has various pharmacological actions, including hypolipidaemic, hypocholesterolaemic and anti-atherosclerotic effects, in experimental animals but the molecular mechanisms involved remain unclear. Here, we investigated changes in the expression of lipid metabolism-associated genes in the liver of RJ-treated mice by means of a DNA microarray technique to obtain clues to the mechanism of the hypocholesterolaemic action of RJ…
RJ decreased gene expression of squalene epoxidase (SQLE), which is a key enzyme in cholesterol biosynthesis, and sterol regulatory element-binding protein (SREB)-1, which may be a transcriptional factor of SQLE. It increased gene expression of low-density lipoprotein receptor (LDLR), which is involved in cholesterol incorporation in liver. Thus, the hypocholesterolaemic action of RJ appears to be associated with a decrease of SQLE and an increase of LDLR in mice.
Journal of Pharmacy and Pharmacology, 2006 Dec;58(12):1683-9
Royal jelly (RJ) has various pharmacological actions, including hypolipidaemic, hypocholesterolaemic and anti-atherosclerotic effects, in experimental animals but the molecular mechanisms involved remain unclear. Here, we investigated changes in the expression of lipid metabolism-associated genes in the liver of RJ-treated mice by means of a DNA microarray technique to obtain clues to the mechanism of the hypocholesterolaemic action of RJ…
RJ decreased gene expression of squalene epoxidase (SQLE), which is a key enzyme in cholesterol biosynthesis, and sterol regulatory element-binding protein (SREB)-1, which may be a transcriptional factor of SQLE. It increased gene expression of low-density lipoprotein receptor (LDLR), which is involved in cholesterol incorporation in liver. Thus, the hypocholesterolaemic action of RJ appears to be associated with a decrease of SQLE and an increase of LDLR in mice.
Saturday, March 03, 2007
U.S. Group Forms to Promote Health Benefits of Honey
A group of American beekeepers, scientific experts and honey packers, producers and importers recently formed the “Committee for the Promotion of Honey and Health in America.”
Part of the committee’s mission is to enhance the image of honey by incorporating contemporary scientific and medical information about the role that honey can play in the human diet and its positive effect on human health. It will also seek to maintain an international perspective regarding support for both standards and research on honey’s health benefits.
The committee plans to publish a series of articles highlighting those benefits, create a speakers bureau and organize an international symposium to address the topic of honey and health from a scientific perspective.
Anyone who would like to support the efforts of the committee should contact Ron Phipps at info@cpnaglobal.com or Ron Fessendon at ron@worldclassemprise.com or by calling 713-865-3145.
Part of the committee’s mission is to enhance the image of honey by incorporating contemporary scientific and medical information about the role that honey can play in the human diet and its positive effect on human health. It will also seek to maintain an international perspective regarding support for both standards and research on honey’s health benefits.
The committee plans to publish a series of articles highlighting those benefits, create a speakers bureau and organize an international symposium to address the topic of honey and health from a scientific perspective.
Anyone who would like to support the efforts of the committee should contact Ron Phipps at info@cpnaglobal.com or Ron Fessendon at ron@worldclassemprise.com or by calling 713-865-3145.
Friday, March 02, 2007
Propolis Components Found to Be Cytotoxic, Strong Antioxidants
New Findings in Cancer Cell Biology Described from National Taiwan University, Graduate Institute of Biochemistry and Molecular Biology
Obesity, Fitness & Wellness Week, 3/10/2007
2007 MAR 10 - (NewsRx.com) -- Research findings, "Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis," are discussed in a new report. "We recently demonstrated that two new prenylflavanones, propolin A and propolin B, isolated and characterized from Taiwanese propolis, induced cytotoxicity effect in human melanoma A2058 cells and shows a strong capability to scavenge free radicals. In this study, propolin A effectively induced a cytotoxic effect on five different cancer cell lines," scientists in Taipei, Taiwan report...
The researchers concluded: "All these results indicated that propolin A and propolin B may trigger apoptosis of A2058 cells through mitochondria-dependent pathways and also shown that propolin A and propolin B were strong antioxidants."
Chen and colleagues published their study in Cancer Letters (Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis. Cancer Letters, 2007;245(1-2):218-31).
For more information, contact C.N. Chen, Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Section 1, Jen-Ai Road, Taipei 100, Taiwan, ROC.
Obesity, Fitness & Wellness Week, 3/10/2007
2007 MAR 10 - (NewsRx.com) -- Research findings, "Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis," are discussed in a new report. "We recently demonstrated that two new prenylflavanones, propolin A and propolin B, isolated and characterized from Taiwanese propolis, induced cytotoxicity effect in human melanoma A2058 cells and shows a strong capability to scavenge free radicals. In this study, propolin A effectively induced a cytotoxic effect on five different cancer cell lines," scientists in Taipei, Taiwan report...
The researchers concluded: "All these results indicated that propolin A and propolin B may trigger apoptosis of A2058 cells through mitochondria-dependent pathways and also shown that propolin A and propolin B were strong antioxidants."
Chen and colleagues published their study in Cancer Letters (Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis. Cancer Letters, 2007;245(1-2):218-31).
For more information, contact C.N. Chen, Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Section 1, Jen-Ai Road, Taipei 100, Taiwan, ROC.
Thursday, March 01, 2007
New Book Analyses the Body’s Response to a Bee Sting
The Pain EventBy Katherine Pushkar, The New York Post (USA), 3/1/2007
March 1, 2007 -- 'Grey's Anatomy" may be sexy but - in spite of its textbook title - it's hardly educational. If you actually want to learn something about the human - as opposed to the Hollywood - body, pick up a copy of "Ouch!: How Your Body Makes It Through a Very Bad Day."
The meticulously and disturbingly detailed book illustrates what happens to the body experiencing a sneeze, a sunburn, a cut. "We wanted to look at things a bit differently," says author Richard Walker by phone from his London home. "We wanted to show how the body defends itself and fights against attack."…
Bee sting
A humble bee sting produces nothing short of chemical warfare. The sting cuts through the top layer of skin, where pain receptors spring into action. The receptors trigger nerve impulses that travel quickly to the brain along tiny cables called nerve fibers. This is when you feel pain. At this point, the arteries, which carry oxygen-rich blood to the skin, widen to increase blood flow to the wound, and this extra blood brings germ-killers and healing properties, diluting the bee venom.
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