Propolis Prevents the Effects of Chronic Alcohol Intake on Ocular Tissues
Ophthalmic Res, 2009 Jul 23;42(3):147-151
This study is designed to investigate the protective effects of propolis in ocular tissues against chronic alcohol exposure.
Material and Method: Wistar albino rats were used in this study. Rats were divided into 4 groups, and each group was fed a special liquid diet which contained an equal amount of calories. The control group was fed the liquid special diet without alcohol and propolis. We added propolis (150 mg/kg) to the diet of the second group. The diet of the third group contained alcohol, the concentration of which was increased progressively. The fourth group was fed a diet including propolis and alcohol…
Results: In the histological investigation of ocular tissues, alcohol caused an increase in thickness of the cornea and corneal epithelium compared to the control group. This incremental tendency was significantly reduced by propolis, and values were very close to those of the control group. Alcohol did not cause any significant alteration of rat retinal thickness.
Conclusion: This study showed that propolis is highly effective against corneal edema secondary to chronic alcohol intake.