Propolis, a Natural Remedy Against Cancer?
Apitherapy Review, Summer 2009
In the last three decades, our understanding of cancers has undergone a fundamental change by the discovery of the genes responsible for the development of these conditions. Nowadays research focuses seriously on the transducers of these genes and more specifically of the PAK1. The PAK 1 is understood to be responsible for the activation of molecules fostering cellular division, the invasion of the body by the tumor, the survival of cancer cells and the development of blood vessels within the tumor.
Current research addresses the development of PAK1 blocking medications…
The synthesis of PAK1-blocking substances will take years. This is the reason why research turns more and more towards natural products already available on the market, which will demonstrate this anti PAK1 capacity, with the hope to make this new therapeutic approach available as quickly as possible to patients suffering from cancers and from neurofibromatosis.
Of these natural products, one of the most promising seems to be the green propolis of Brazil, rich in Artepillin C, a PAK1- blocking agent.
Propolis, a PAK1- blocking agent
Propolis is a resinous substance produced by exudation from plants and collected by bees, who use it in the hive.
It includes some 300 components, mainly resin (50%), wax (30%), essential oils (10%), pollen (5%), together with a whole series of other organic components (5%). Amongst these organic components one can identify phenolic components, esters, flavonoids, terpenes, beta-steroids, aldheids and aromatic alcohols.
In traditional medicine, propolis is known for having a large spectrum of biological and therapeutic properties with anti-hepatotoxic, anti-inflammatory and antioxidant activities.  And now, one of its most promising medical properties, internationally actively studied, is its anti-cancerous effect. Like any natural substance, its composition is directly dependent on different factors, such as its botanical origin and the environmental conditions of its development. Green propolis of Brazil (GPB) is the only one having in its composition 6 to 8% Artepillin C (ARC)…
As their research progresses, scientific researchers seem to discover an ever larger power to Artepillin C. It could be that, taken at an early stage, this molecule might be the remedy for cancer: More than 70% of cancers are PAK1 dependant and Artepillin C appears to be a very efficacious blocking agent of PAK1.
Green propolis of Brazil, very rich in Artepillin C, is therefore expected to be a natural remedy against cancer. As it is PAK1 blocking and easily absorbed by the organism, it seems active when taken orally and might even present an inhibitory effect vis a vis certain cancers, if taken daily.