A systematic review and meta-analysis by Cozma et al. (4) resulted in some important findings with respect to the effect of fructose in diabetic patients. The authors concluded that compared to other carbohydrates, fructose has greater long term benefits for improving glycemic control and has no effect on insulin and fasting glucose. Moreover, unlike the work of Bahrami et al. (3), this study showed improvements in HbA1c levels as a result of fructose consumption. However, this review has several limitations, including the short duration (less than 12 weeks) and relatively low quality of most trials analyzed. Thus, larger and longer studies are recommended.