Successful treatment of persistent Clostridium difficile infection with manuka honey
Int J Antimicrob Agents. 2017 Feb 28
Clostridium difficile-associated disease is an increasingly common health problem. C. difficile is a causative agent of antibiotic-associated pseudomembranous colitis, antibiotic-associated colitis and antibiotic-associated diarrhoea. C. difficile overgrowth usually occurs during antibiotic therapy as the normal gastrointestinal flora is disrupted. Discontinuation of antibiotics does not lead to symptomatic improvement, and new strains of the pathogen have a substantial failure rate after therapy cessation.