Bee Venom Allergens May Help Produce Preventive Allergy Vaccine

Researchers from Japan, Brazil and Switzerland Report Recent Findings in Allergies
Science Letter, 6/23/2006

Allergies research advances have been reported from Japan, Brazil and Switzerland…

Study 3: A recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes prevents allergy attacks.

According to recent research published in the European Journal of Immunology, "Novel approaches for the prevention of allergy are required, because of the inevitably increasing prevalence of allergic diseases during the last 30 years."

Fariba Karamloo at the Swiss Institute of Allergy and Asthma Research and collaborators throughout the world announced, "A recombinant chimeric protein, which comprises the whole amino acid sequences of three bee venom major allergens has been engineered and used in prevention of bee venom sensitization in mice."...

Karamloo and associates published their study in the European Journal of Immunology (Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes. Eur J Immunol, 2005;35(11):3268-3276).

For additional information, contact Fariba Karamloo, Swiss Institute of Allergy and Asthma Research (SIAF), Obere Strasse 22, CH-7270 Davos, Switzerland. karamlooflory@compuserve.de.