In Vitro Antimicrobial Activity of Natural Toxins and Animal Venoms Tested Against Burkholderia Pseudomallei
BMC Infect Dis., 2006 Jun 20;6(1):100
BACKGROUND: Burkholderia pseudomallei are the causative agent of melioidosis. Increasing resistance of the disease to antibiotics is a severe problem in treatment regime and has led to intensification of the search for new drugs. Antimicrobial peptides are the most ubiquitous in nature as part of the innate immune system and host defense mechanism.
METHODS: Here, we investigated a group of venoms (snakes, scorpions and honey bee venoms) for antimicrobial properties against two strains of Gram-negative bacteria Burkholderia pseudomallei by using disc diffusion assay for in vitro susceptibility testing…
RESULTS: The studied venoms showed high antimicrobial activity…
Friday, June 30, 2006
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