Microarray Analysis of Gene Expression Profiles in Response to Treatment with Bee Venom in Lipopolysaccharide Activated RAW 264.7 CellsJ Ethnopharmacol, 2008 Sep 18
Aim of the Study: The therapeutic application of bee venom (BV) has been used in traditional medicine to treat diseases such as arthritis, rheumatism and pain. Macrophages produce molecules that are known to play roles in inflammatory responses...
… BV inhibited the expression of specific inflammatory genes…
Conclusions: These results demonstrate the potent activity of BV as a modulator of the LPS-mediated nuclear factor-kappaB (NF-kappaB)/MAPK pathway in activated macrophages. In addition, these results can be used to understand other effects of BV treatment.
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