Apoptosis of Human Breast Cancer Cells Induced by Ethylacetate Extracts of PropolisAmerican Journal of Biochemistry and Biotechnology, 6(2): 84-88, 2010
Problem statement: Propolis has been ethno medically claimed to possess a wide array of biological activities including anticancer activity. The purpose of this research was to verify the folklore claim.
Approach: This study was performed in a human breast carcinoma cell, MCF-7. Extract of propolis from different solvent, ethylacetate and n-buthanol showed induced apoptotic cells was detected by flow cytometry.
Results: The results demonstrated that ethylacetate extract of propolis can induce apoptosis in MCF-7 as large as 13.21% during the 24 h incubation. On the other hand, doxorubicin is able to induce apoptosis as large as 18.89% during the 24 h incubation.
Conclusion: The extracts of propolis ethylacetate had cytotoxic activity and triggers apoptosis on MCF-7 cells.
2 comments:
this information could be so valuable could some one please translate it?
It appears that Propolis extracted by an ethyl-alcohol solution, worked nearly as well as Doxorubicin on these particular cancer cells.
From Wikipedia, "Doxorubicin is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.
Doxorubicin's most serious adverse effect is life-threatening heart damage."
Propolis, on the other hand, doesn't pose any health risks and has been identified in numerous studies to be an effective anti-tumor, anti-carcinogenic product. I'm not a doctor, but an Apitherapist and I prefer to use a natural product which is complimentary and not adverse to the body's ability to heal itself.
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