Lactic Acid Bacterial Symbionts in Honeybees - An Unknown Key to Honey's Antimicrobial and Therapeutic Activities
Int Wound J. 2014 Sep 8. doi: 10.1111/iwj.12345
We demonstrate a strong antimicrobial activity from each symbiont and a synergistic effect, which counteracted all the tested pathogens. The mechanisms of action are partly shown by elucidating the production of active compounds such as proteins, fatty acids, anaesthetics, organic acids, volatiles and hydrogen peroxide. We show that the symbionts produce a myriad of active compounds that remain in variable amounts in mature honey. Further studies are now required to investigate if these symbionts have a potential in clinical applications as alternative tools against topical human and animal infections.