Ann Burns Fire Disasters, 2014 Mar 31;27(1):22-30
Made by bees from the nectar of flowers, used since ancient times to treat wounds and burns, honey has lately acquired a growing interest from the international scientific community and has been the subject of many specialized studies and communications. This article highlights the up-to-date knowledge on qualities, properties and mode of appliance of honey in the treatment of wounds of various etiologies, particularly burns, through an extensive retrospective analysis of data from the literature. This article aims to review and provide a synthesis of current issues regarding the complex action of honey on burn wounds, evidenced by in vitro studies, laboratory experiments and clinical trials published in the specialized literature. The present work analyzes extensively the anti-infectious and anti-inflammatory properties of honey, as well as its favorable effect on wound regeneration. Effectiveness of topical administration of honey is evidenced both by a series of experiments on laboratory animals and by clinical trials. This article also draws the attention of both medical staff and patients to the possibility of using this product, and to its acceptability in practice…
In vitro and in vivo studies have highlighted a broad range of activities provided by honey in burn treatment. These include anti-infectious, anti-inflammatory, antiexudative, antioxidant, wound healing, wound debriding and nutritional properties. In evidence-based medicine, research and clinical studies have shown the efficiency of honey in superficial and partial thickness burns therapy, when compared to other dressing products, making it a viable option as a valuable topical agent in clinical practice. However, as honey also appears to delay healing of partial and full thickness burns when compared to surgical treatment (early excision and grafting), its use requires further exploration. More detailed controlled trials are required to establish the best indications, methods and modalities of honey administration for each type and stage of burn. It is also necessary to have criteria for honey selection over other forms of treatment in burn management, which, of course, will also depend on the preferences and experience of those involved.