Dear editor, we would like to discuss on the publication on “Honey Dressing vs. Povidone Iodine Dressing .” Gulati et al. concluded that “Honey dressing is highly effective in achieving healing in chronic wounds as compared to Povidone iodine dressing .” In fact, the usefulness of honey in wound care is acceptable and honey is widely used. It is approved for the antibacterial activity and proposed to be a good therapeutic agent for infectious diseases . However, the important consideration is the possible contamination of honey. Honey is reported for high contamination by Clostridium pathogen that can cause botulism . To use honey in surgery, good preparation and sanitation control is needed.