Clin Otolaryngol. 2016 Nov 12
Honey reduced post-tonsillectomy pain, but its effects on awakening at night, inflammation and healing of the tonsillar fossa were controversial.
This systematic review and meta-analysis of randomized controlled trials (RCTs) evaluated the effect of oral honey on pain, consumption of painkillers, awakening at night, healing of tonsillar fossa, and adverse effects in children after tonsillectomy.
A search of MEDLINE, EMBASE, SCOPUS, CINAHL and COCHRANE Collaboration library databases was performed without any restriction of publication year. The end date of search was June 30, 2016. The search was supplemented by search from Google, hand search of cross-references of selected articles and reviews, and contacting the authors of different studies. The inclusion criteria were RCTs comparing the effect of honey with control on different outcomes, in children after tonsillectomy.
Honey improved pain, requirement of painkillers, and awakening at night due to pain in children after tonsillectomy. There was little improvement in healing of tonsillar fossa. The GRADE of the evidence varied from 'low' to 'very low'. A good quality, placebo controlled RCT of different doses and durations of administration of honey is required to evaluate its clear efficacy and safety in children after tonsillectomy. This article is protected by copyright. All rights reserved.