Ischemia-Reperfusion Injury Reduced by Caffeic Acid Phenethyl Ester in Mice
Science Letter, 5/1/2006
(NewsRx.com) -- Caffeic acid phenethyl ester (CAPE) treatment inhibits ischemia-reperfusion injury in mice.
"Oxygen-derived free radicals have been implicated in the pathogenesis of tissue injury after ischemia-reperfusion," reconstructive surgeons in Turkey explained.
CAPE, "an active ingredient of honeybee propolis, has been identified as having potent antioxidant and anti-inflammatory properties," noted B.T. Bilen and colleagues at Turgut Ozal Medical Center in Malatya.
In a recent study, they "evaluated the ability of CAPE applied intraperitoneally in reducing tissue injury after ischemia-reperfusion."…
"CAPE given intraperitoneally had an inhibitory effect on tissue injury after ischemia-reperfusion comparable to that of a control group," test results revealed…
Bilen and coauthors published their study in the Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery (Effect of caffeic acid phenethyl ester on survival of axial pattern flaps in rats with ischaemia-reperfusion injuries. Scand J Plast Reconstr Surg Hand Surg, 2006;40(2):73-78)…
Saturday, April 29, 2006
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