Honey May Protect Against Cardiac Disorders

Cardioactive and Vasoactive Effects of Natural Wild Honey Against Cardiac Malperformance Induced by Hyperadrenergic Activity
Journal of Medicinal Food, March 1, 2008, 11(1): 91-98

Abstract: Induction of hyperadrenergic activity was experimentally achieved in urethane-anesthetized rats using epinephrine (adrenaline). Acute administration of epinephrine (100 g/kg) for 2 hours induced several cardiac disorders and vasomotor dysfunction. Pretreatment with natural wild honey (5 g/kg) for 1 hour prior to the injection with epinephrine (100 g/kg) protected the anesthetized normal rats from the incidence of epinephrine-induced cardiac disorders and vasomotor dysfunction.

Moreover, posttreatment with natural wild honey (5 g/kg) following the injection with epinephrine (100 g/kg) for 1 hour showed several ameliorative outcomes to the electrocardiographic parameters and vasomotor dysfunction of anesthetized stressed rats...

It would appear from the results of the present study that natural wild honey may exert its cardioprotective and therapeutic effects against epinephrine-induced cardiac disorders and vasomotor dysfunction directly, via its very pronounced total AOC and its great wealth of both enzymatic and nonenzymatic antioxidants involved in cardiovascular defense mechanisms...