Suppressive Effects of Bee Venom on the Immune Responses in Collagen-Induced Arthritis in RatsPhytomedicine, 2008 Apr 16
The effect of bee venom (BVA) on the development of type II collagen (CII)-induced arthritis (CIA) in rats has been studied…
Pretreatment of rats with BVA could inhibit the development of collagen arthritis even when 10-20mul/100g/day of the BVA were used for pretreatment. Interestingly, higher doses than 10mulBVA/100g mouse were much effective for arthritis incidence.
Treatment of rats with BVA prevented the development of collagen arthritis in a dose-dependent manner. Doses of BVA (15 and 20mul/100g) resulted in decreased incidence of arthritis.
In conclusion, therapeutic i.p injection with BVA improved the clinical course of the disease and the immune response to CII.
No comments:
Post a Comment