Methylglyoxal: A New Weapon against Staphylococcal Wound Infections?
Chemistry Letters, Vol. 39 (2010) , No. 4 p.322
Methylglyoxal (MG), a phytochemical present in some New Zealand honeys, was found to possess bactericidal activity against S. aureus and a methicillin-resistant strain of S. epidermidis. The MIC and MBC values were 1.05 and 2.11 mM, respectively. Inclusion of MG in a hydrogel resulted in an active and stable preparation suitable for treating wound or burn infections.