Recent Research on 3-Phenyllactic Acid, a Broad-Spectrum Antimicrobial Compound
Appl Microbiol Biotechnol, 2012 Jul 12
3-Phenyllactic acid (PLA), which is an organic acid widely
existing in honey and lactic acid bacteria fermented food, can be produced by
many microorganisms, especially lactic acid bacteria. It was proved as an ideal
antimicrobial compound with broad and effective antimicrobial activity against
both bacteria and fungi. In addition, it could be used as feed additives to
replace antibiotics in livestock feeds.
This article presented a review of recent studies on the
existing resource, antimicrobial activity, and measurement of PLA. In addition,
microorganism strains and dehydrogenases producing PLA were reviewed in detail,
the metabolic pathway and regulation of PLA synthesis in LAB strains were
discussed, and high-level bioproduction of PLA by microorganism fermentation
was also summarized.
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