Friday, May 17, 2013

Royal Jelly Prevents Age-Related Loss of Muscle Mass


Royal Jelly Prevents the Progression of Sarcopenia in Aged Mice In Vivo and In Vitro
Sarcopenia is characterized by the age-related loss of muscle mass and strength. One of the mechanisms of sarcopenia is the loss in the function and number of muscle satellite cells.
Royal jelly (RJ) is a health food used worldwide. To obtain better digestion and absorption than RJ, protease-treated RJ (pRJ) has been developed. RJ and pRJ have been suggested to have potential pharmacological benefits such as prolonging the life span and reducing fatigue. Because these effects may improve sarcopenia and the functions of satellite cells, we examined the effects of RJ or pRJ treatment on the skeletal muscles in an animal model using aged mice.
In vivo, RJ/pRJ treatment attenuated the decrease in the muscle weight and grip strength and increased the regenerating capacity of injured muscles and the serum insulin-like growth factor-1 levels compared with controls. In vitro, using isolated satellite cells from aged mice, pRJ treatment increased the cell proliferation rate, promoted cell differentiation, and activated Akt intracellular signaling pathway compared with controls.
These findings suggest that RJ/pRJ treatment had a beneficial effect on age-related sarcopenia.

1 comment:

Biddut Debnath said...

Hi, Are you well?

Hey, you have included very well article on here on here about. I really like this type’s content. I also like to inform Looking for Community submitting of public bookmarks Submissions? Get inexpensive Community submitting of public bookmarks Syndication Provides. Find the best Manual social bookmarking service Provides these days.

Thanks For Only You Create That cute Article.