Propolis Has ‘Potentially Useful’ Role in Treatment of Periodontal Disease

Periodontal Disease Therapy
Pharma Investments, Ventures & Law Weekly, 9/16/2007

New research, "Semisolid systems containing propolis for the treatment of periodontal disease: in vitro release kinetics, syringeability, rheological, textural, and mucoadhesive properties," is the subject of a report.

"Formulations containing poloxamer 407 (P407), carbopol 934P (C934P), and propolis extract (PE) were designed for the treatment of periodontal disease. Gelation temperature, in vitro drug release, rheology, hardness, compressibility, adhesiveness, mucoadhesion, and syringeability of formulations were determined," investigators in Ribeirao Preto, Brazil report…

The researchers concluded: "The data obtained in these formulations indicate a potentially useful role in the treatment of periodontitis and suggest they are worthy of clinical evaluation."

Bruschi and colleagues published their study in the Journal of Pharmaceutical Sciences (Semisolid systems containing propolis for the treatment of periodontal disease: in vitro release kinetics, syringeability, rheological, textural, and mucoadhesive properties. Journal of Pharmaceutical Sciences, 2007;96(8):2074-89).