Tuesday, July 25, 2023

Honey Has Protective Effect in Cerebrovascular Diseases

Apitherapy in Post-Ischemic Brain Neurodegeneration of Alzheimer’s Disease Proteinopathy: Focus on Honey and Its Flavonoids and Phenolic Acids

Molecules 2023, 28(15), 5624

Neurodegeneration of the brain after ischemia is a major cause of severe, long-term disability, dementia, and mortality, which is a global problem. These phenomena are attributed to excitotoxicity, changes in the blood–brain barrier, neuroinflammation, oxidative stress, vasoconstriction, cerebral amyloid angiopathy, amyloid plaques, neurofibrillary tangles, and ultimately neuronal death. In addition, genetic factors such as post-ischemic changes in genetic programming in the expression of amyloid protein precursor, β-secretase, presenilin-1 and -2, and tau protein play an important role in the irreversible progression of post-ischemic neurodegeneration. Since current treatment is aimed at preventing symptoms such as dementia and disability, the search for causative therapy that would be helpful in preventing and treating post-ischemic neurodegeneration of Alzheimer’s disease proteinopathy is ongoing. Numerous studies have shown that the high contents of flavonoids and phenolic acids in honey have antioxidant, anti-inflammatory, anti-apoptotic, anti-amyloid, anti-tau protein, anticholinesterase, serotonergic, and AMPAK activities, influencing signal transmission and neuroprotective effects. Notably, in many preclinical studies, flavonoids and phenolic acids, the main components of honey, were also effective when administered after ischemia, suggesting their possible use in promoting recovery in stroke patients. This review provides new insight into honey’s potential to prevent brain ischemia as well as to ameliorate damage in advanced post-ischemic brain neurodegeneration.

Monday, July 24, 2023

Australian Beekeepers Look to Untapped Health Potential of Propolis - #ABCNewsAustralia

ABC News

A by-product of honey production largely discarded in Australia could provide an alternative income source for beekeepers across the country.

Hidden within the walls of their hives, bees blend up a unique mix of materials that scientists believe holds untapped potential in Australia.

Propolis is a sticky, resinous substance that's sometimes referred to as "bee glue."

Sunday, July 23, 2023

UK Launches First Apitherapy Center

The UK’s first ‘bee therapy’ retreat just launched in Perthshire, with sounds, vibrations and aromas to help visitors de-stress and chill out. I was buzzing to check it out. Here’s how I got on.

The Courier.

Tuesday, July 18, 2023

Oxymel Honey-Vinegar Combo Boosts Wound Healing

Oxymel: Scientists say honey and vinegar is a wound-healing power couple


A combination of honey and vinegar has shown promise as a treatment for wound infections, researchers in the UK have discovered.

Our ancestors were onto something when they used honey and vinegar to heal and clean wounds.

Like so many things, these remedies got lots amongst modern practices, but now Warwick University in the UK has discovered the true power behind these natural foods as topical medicines.

In the university’s Sweet and Sour Synergy study, researchers underwent the first comprehensive study of its kind, and what they found was that yes, elements of honey and vinegar have incredible wound healing properties, but when combined in low doses, are even more powerful. This combination is called oxymel.

Monday, July 17, 2023

Video: Bee Venom Therapy Popular in Kenya

Murang'a residents turn to apitherapy; testify to being healed after getting stings

Monday, July 10, 2023

Propolis and its constituents exhibit anti-obesity, anti-hypertension, anti-dyslipidemic, anti-atherosclerosis, and anti-diabetic effects

Propolis and its constituents against cardiovascular risk factors including obesity, hypertension, atherosclerosis, diabetes, and dyslipidemia: A comprehensive review

Review Iran J Basic Med Sci. 2023;26(8):853-871

Cardiovascular diseases (CVDs) are some of the major causes of death worldwide. The modern lifestyle elevates the risk of CVDs. CVDs have several risk factors such as obesity, dyslipidemia, atherosclerosis, hypertension, and diabetes. 

Using herbal and natural products plays a pivotal role in the treatment of different diseases such as CVDs, diabetes, and metabolic syndrome. Propolis, a natural resinous mixture, is made by honey bees. Its main components are phenolics and terpenoid compounds such as caffeic acid phenethyl ester, chrysin, and quercetin. 

In this review, multiple studies regarding the pharmacological impacts of propolis and its constituents with their related mechanisms of action against mentioned CVD risk factors have been discussed in detail. Here, we used electronic databases or search engines such as Scopus, Web of Science, Pubmed, and Google Scholar without time limitations. 

The primary components of propolis are phenolics and terpenoid compounds such as caffeic acid phenethyl ester, chrysin and quercetin. Propolis and its constituents have been found to exhibit anti-obesity, anti-hypertension, anti-dyslipidemic, anti-atherosclerosis, and anti-diabetic effects. 

The vast majority of studies discussed in this review demonstrate that propolis and its constituents could have therapeutic effects against mentioned CVD risk factors via several mechanisms such as antioxidant, anti-inflammatory, reducing adipogenesis, HMG-CoA reductase inhibitory effect, inhibition of the ACE, increasing insulin secretion, NO level, etc.