Brazilian Green Propolis Inhibits Inflammatory Angiogenesis in a Murine Sponge Model
Evid Based Complement Alternat Med, Published online on December 9, 2009
Angiogenesis and inflammation are persistent features of several pathological conditions. Propolis, a sticky material that honeybees collect from living plants, has been reported to have multiple biological effects including anti-inflammatory and anti-neoplasic activities.
Here, we investigated the effects of water extract of green propolis (WEP) on angiogenesis, inflammatory cell accumulation and endogenous production of cytokines in sponge implants of mice over a 14-day period…
Our results indicate that the anti-inflammatory/anti-angiogenic effects of propolis are associated with cytokine modulation.