Effect of Honey on Nocturnal Cough and Sleep Quality: A
Double-blind, Randomized, Placebo-Controlled Study
Pediatrics, 2012 Aug 6
OBJECTIVES:
To compare the effects of a single nocturnal dose of 3 honey
products (eucalyptus honey, citrus honey, or labiatae honey) to placebo (silan
date extract) on nocturnal cough and difficulty sleeping associated with
childhood upper respiratory tract infections (URIs).
METHODS:
A survey was administered to parents on 2 consecutive days,
first on the day of presentation, when no medication had been given the
previous evening, and the following day, when the study preparation was given
before bedtime, based on a double-blind randomization plan. Participants
included 300 children aged 1 to 5 years with URIs, nocturnal cough, and illness
duration of ≤7 days from 6 general pediatric community clinics. Eligible
children received a single dose of 10 g of eucalyptus honey, citrus honey, labiatae
honey, or placebo administered 30 minutes before bedtime. Main outcome measures
were cough frequency, cough severity, bothersome nature of cough, and child and
parent sleep quality.
RESULTS:
In all 3 honey products and the placebo group, there was a
significant improvement from the night before treatment to the night of
treatment. However, the improvement was greater in the honey groups for all the
CONCLUSIONS:
Parents rated the honey products higher than the silan date
extract for symptomatic relief of their children's nocturnal cough and sleep
difficulty due to URI. Honey may be a preferable treatment for cough and sleep
difficulty associated with childhood URI.
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