Evid Based Complement Alternat Med, 2013;2013:254017
An investigation of effectiveness of topical treatment of
nonhealing chronic venous leg ulcers with propolis ointment was conducted. 56
patients were included in the study and randomized into two groups.
In group 1, there were 28 patients (ulceration area:
6.9-9.78 cm(2)) treated by means of topical propolis ointment application and
short stretch bandage compression. In group 2, there were 29 patients
(ulceration area: 7.2-9.4 cm(2)) treated by means of Unna boot leg compression
without topical propolis treatment. In the study, the efficacy of both
treatment methods in patients with resistive venous leg ulcers was compared.
The ulceration of patients from group 1 healed completely
after 6 weeks of therapy in all cases. In all patients from group 2, the process
of healing was longer but successfully completed after 16 weeks of the therapy.
We found that an adjunctive propolis ointment treatment
increases the efficacy of the short stretch bandage compression stocking, and
this combined treatment is more effective than Unna's boot compression alone.
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