Sunday, April 23, 2006

Propolis Research: Side Effects, Anti-Tumor Potential

Propolis: Effect of Different Concentrations, Extracts and Intake period on Seric Biochemical Variables
Journal of Ethnopharmacology, Volume 105, Issues 1-2 , 21 April 2006, Pages 95-98

Conclusion: On the basis of our findings, since propolis does not induce any significant change in seric parameters, it is claimed that long-term administration of propolis might not have any cardiac injury.

Inhibitory Effect of Caffeic Acid Phenethyl Ester on the Growth of C6 Glioma Cells In Vitro and In Vivo
Cancer Letters, Volume 234, Issue 2 , 28 March 2006, Pages 199-208

Conclusion: These results suggest that CAPE presents an antitumor potential for glioma by inhibiting the growth of tumor cells.

Synthesis of Compounds with Antiproliferative Activity as Analogues of Prenylated Natural Products Existing in Brazilian Propolis
European Journal of Medicinal Chemistry, Volume 41, Issue 3 , March 2006, Pages 401-407

Conclusion: The compounds were tested for their cytotoxicity toward a diverse panel of cultured human tumor cell lines. Compound 3 showed significant selective cytotoxic activity (IC50 < 9 μg/ml).

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