Wednesday, December 12, 2018

Propolis Extract Cures Fungal Nail Infections (Onychomycosis)


Propolis for the Treatment of Onychomycosis

Indian J Dermatol. 2018 Nov-Dec;63(6):515-517

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Onychomycosis is a fungal nail infection, considered as a public health problem because it is contagious and it interferes with the quality of life. It has long and difficult treatment, with many side effects and high cost. Propolis extract (PE) is a potential alternative to conventional antifungal agents because it has low cost, accessibility, and low toxicity. Herein, we report the favorable response of PE in onychomycosis in three elderly patients...

In our in vitro experiments, PE was able to inhibit Candida spp. like other cases in the literature. In vivo, four nails were treated with PE of which two of them showed complete resolution. Culture was negative. The other two nails showed a reduction of over 50% of the lesion; however, fungi were still isolated. Based on the results obtained during in vitro studies as well as results obtained from tests performed after topical treatment, it can be concluded that propolis possesses antifungal potential and is a promising therapeutic option in cases of onychomycosis.

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