A Morphometric and Histopathological Evaluation of the Effects of Propolis on Alveolar Bone Loss in Experimental Periodontitis in RatsJournal of Periodontology, Posted online on May 15, 2008
Aim: Propolis collected by honeybees from various plant sources is a resinous hive product possessing a broad spectrum of biological activities. Propolis, has been extensively used in diet to improve health and to prevent disease. The purpose of this study was to analyze the morphometric and histopathological changes associated with experimental periodontitis in rats in response to systemic administration of propolis…
Results: At the end of 11 days alveolar bone loss significantly higher in the LO group compared to the NL, Pro100, and Pro200 groups. Osteoclast number of the LO group was significantly higher than those of the NL, Pro100 and Pro200 groups. Both doses of propolis significantly reduced the periodontitis-related bone loss, but the differences between two propolis groups were not statistically significant.
Conclusion: The findings of this study provide morphological and histological evidence that propolis, when administered systemically, prevents alveolar bone loss in the rat model.
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