Saturday, June 14, 2008

Propolis Shows ‘Significant Hepatoprotective Effect’

Effect of Propolis on Oxidative Stress and Histomorphology of Liver Tissue in Experimental Obstructive Jaundice
Eur Surg Res, 2008;41:231-237

Background: Propolis is a natural product collected by honey bees from various plant sources. We aimed to determine the possible effects of propolis on oxidative stress and hepatocyte apoptosis in experimental obstructive jaundice.

Results: The plasma and liver levels of MDA were significantly lower in the propolis group than in the BDL group…In the propolis group, the enlargement of hepatocytes, dilatation of canaliculi and the edema regressed. The regenerating and normal hepatocytes were demonstrated. In the TUNEL assay, propolis administration reduced hepatocyte apoptosis.

Conclusion: Propolis showed a significant hepatoprotective effect in this experimental obstructive jaundice model.

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