Sunday, August 09, 2015

Honey a Novel Antigiardial Agent

Antigiardial activity of glycoproteins and glycopeptides from Ziziphus honey  

Natural Product Research: Formerly Natural Product Letters 
Natural honey contains an array of glycoproteins, proteoglycans and glycopeptides. Size-exclusion chromatography fractionated Ziziphus honey proteins into five peaks with molecular masses in the range from 10 to >200 kDa. The fractionated proteins exhibited in vitro activities against Giardia lamblia with IC50 values ≤ 25 μg/mL.

Results indicated that honey proteins were more active as antiprotozoal agents than metronidazole. This study indicated the potential of honey proteins and peptides as novel antigiardial agents.

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