Thursday, February 22, 2018

Propolis Component Pinocembrin is an Antioxidant and Anti-Inflammatory Molecule

Pinocembrin And Its Effect On Mitochondria

Science Trends

Pinocembrin, which is also known as 5,7-dihydroxyflavone (C15H12O4), has been obtained from plants such as Eucalyptus and Pinus heartwood. Pinocembrin is found in propolis, which is widely consumed by humans due to its medicinal properties. Actually, pinocembrin is a major component of propolis. It has been reported that pinocembrin induces cytoprotective effects in human cells.

Pinocembrin is an antioxidant and anti-inflammatory molecule, meaning that it acts against the deleterious effects elicited by reactive species/free radicals and attenuates inflammation. Some researchers also described an anti-tumor action of pinocembrin experimentally. Recently, our research group published a paper showing that pinocembrin is able to cause mitochondrial protection in the SH-SY5Y human neuroblastoma cell line...

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