Monday, December 18, 2006

Study: Propolis Decreases Heart Mitochondrial Respiration Rate

Findings in Cardiology Reported from Lithuania and France
Cardiovascular Week, 12/18/2006

Researchers in Lithuania report, "The effect of propolis water solution (PWS) on the respiration of rat heart mitochondria with NAD-linked (pyruvate + malate), FAD-linked (succinate) substrates and fatty acids (palmitoyl-L-carnitine) was investigated in this study."

"PWS at the lowest concentration of 4 mcg mL-1 of phenolic compounds (PC) had no effect on mitochondrial respiration with all investigated substrates," wrote D. Majiene and colleagues at Kaunas University of Medicine…

"The PWS-caused decrease in the mitochondrial respiration rate with pyruvate + malate and fatty acids could be due to diminished activities of respiratory chain complexes and/or ADP/ATP translocator," the authors concluded.

Majiene and colleagues published their study in the Journal of Pharmacy and Pharmacology (Influence of propolis water solution on heart mitochondrial function. J Pharm Pharmacol, 2006;58(5):709-713).

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