Friday, March 05, 2010

Compound Extracted from Egyptian Propolis has Antimicrobial Activity

A New Prenylated Flavanoid with Antibacterial Activity from Propolis Collected in Egypt
Nat Prod Commun, 2010 Jan;5(1):43-5

A novel prenylated flavanoid, isonymphaeol-D (1), together with two known compounds, isonymphaeol-B (2) and nymphaeol-B (3), were isolated from Egyptian propolis. The structures of the isolated compounds were determined by various spectroscopic methods. 1 exhibited antibacterial activity against Gram-positive (Bacillus cereus, Staphylococcus aureus) and Gram-negative strains (Serratia sp., Pseudomonos sp., Escherichia coli)...

Conclusions: In this work, new compound was extracted from Egyptian propolis, this compound possess antimicrobial activities for Gram- positive strain and Gram-negative strain using Ampicillin and amoxicillin as refe-rences.

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