Saturday, May 26, 2012

Bee Venom May Help Treat Parkinson’s Disease

Neuroprotective Effects of Bee Venom by suppression of Neuroinflammatory Responses in Mouse Model of Parkinson’s Disease: Role of CD4+CD25+Foxp3+ Regulatory T Cells
The Journal of Immunology, 2012, 188, 119.2
In the present study, we examined whether bee venom (BV) promotes the survival of nigrostriatal dopaminergic (DA) neurons in the MPTP-induced Parkinson’s disease (PD) mice model.
Treatment of BV prevented degeneration of nigrostriatal DA neurons, increased striatal dopamine levels, and improved motor function. This nueroprotection afforded by bee venom was associated with the suppression of microglia and inhibition of recruitment of CD4+ T cells.
Additionally, CD4+CD25+Foxp3+ Treg cells were significantly increased in vivo and in vitro after treatment of BV.
Therefore, we carefully propose that neuroprotection of BV might be associated with its anti-inflammatory properties and could be employed as novel therapeutic agents for PD and other disorders associated with neuroinflammation.

1 comment:

Anonymous said...

I am trying to find out where someone in Illinois could call to get more information on the bee therapy. Is there a clinic, or is it a hospital?