The Inhibitory Activity of Typified Propolis Against Enterococcus
Species
Z Naturforsch C, 2012 May-Jun;67(5-6):249-56
Propolis, a natural bee product widely used for its
antimicrobial activity, was tested against isolates of Enterococcus from
humans, pig-tailed macaques, isolates of refractory endodontic treatment cases,
and isolates from Lactobacillus-containing food supplements.
Typification of the propolis was performed by
high-performance liquid chromatography (HPLC) by which prenylated compounds,
cinnamic acid derivatives, and flavonoids were detected as the main
constituents. Minimum inhibitory concentrations (MIC) were determined using the
agar dilution method.
All human and animal Enterococcus isolates demonstrated MIC
values of 1600 microg/mL. Enterococcal species of human and animal origin were
inhibited by propolis. Particularly, human isolates of E. faecium and E.
faecalis of refractory endodontic treatment cases were susceptible to propolis
of Brazilian origin.
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