Future Microbiol. 2017 Oct 4
AIM:
The present study evaluated the capacity of three species of Fusarium isolated from onychomycosis to form biofilms and the antibiofilm effect of propolis extract on these biofilms.
MATERIALS & METHODS:
The biofilms and antibiofilm effects were evaluated by quantifying the colony-forming units, mitochondrial metabolic activity assays, total biomass by crystal violet staining and scanning electron microscopy.
RESULTS:
Propolis extract demonstrated significant antibiofilm efficiency on Fusarium spp. isolates and reduced F. solani, F. oxysporum and F. subglutinans mature biofilms.
CONCLUSION:
Propolis extract can be an alternative topical treatment of onychomycosis caused by Fusarium spp.
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