Iran Endod J, 2012 Summer;7(3):127-33
This study evaluated and compared colony forming units
(CFUs) and minimum inhibitory concentrations (MICs) of calcium hydroxide and
propolis as intracanal medicaments.
MATERIALS AND METHODS:
Eighty human single-root and caries-free teeth were selected
and divided into five groups. Crowns were removed. Root canals were then
prepared in a step-back manner. The samples were then inoculated by Enterococcus
(E.) faecalis and incubated for 21 days. Intracanal medications were applied
including, calcium hydroxide (n=20), propolis (n=20), and ethanol (n=20). Two
groups of 10 teeth were also used as the positive and negative controls.
Microbiological sampling was performed utilizing a piezo-reamer drill after one
week of incubation. The samples were plated and CFUs were counted after 48
hours. MICs of calcium hydroxide and propolis were measured by serial dilution
and agar dilution methods, respectively. The statistical tests of ANOVA and
Duncan post-hoc were used to compare different medications.
RESULTS:
MICs and CFUs of propolis were dramatically less than
calcium hydroxide. The difference between the groups was statistically
significant.
CONCLUSION:
CONCLUSION:
Our results reveal that propolis is an effective
antimicrobial intracanal agent.
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