Effects of Honey, Sucrose and Glucose on Blood Glucose and C-Peptide in Patients with Type 1 Diabetes Mellitus
Complement Ther Clin Pract, 2013 Feb;19(1):15-9
This study was a case control cross sectional study that was
conducted on 50 patients with type 1 diabetes mellitus and 30 controls without
diabetes. The mean age of patients was 10.02 years.
Oral sugar tolerance tests using glucose, sucrose and honey
and measurement of fasting and postprandial serum C-peptide levels were done
for all subjects in three separate sittings. The glycemic index (GI) and the
peak incremental index (PII) were then calculated for each subject.
Honey, compared to sucrose, had lower GI and PII in both
patients and controls (P < 0.01). In both patients and controls, the
increase in the level of C-peptide after honey was significant when compared
with either glucose or sucrose (P < 0.01).
Conclusion: Because of its possible stimulatory effect on
diseased beta cells, honey might be considered in future therapeutic trials
targeting beta cells of pancreas.
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