Cont Lens Anterior Eye, 2014 Sep 29. pii:
S1367-0484(14)00110-6
The aim of this study was to report the complementary use of
honey for treatment of a contact lens-induced corneal ulcer. A 23-year-old
contact lens user presented with a corneal ulcer in her left eye. She had
visual acuity reduced to hand movement. There was a history of wearing contact
lenses while swimming in a lake seven days before presentation. The cultures
from corneal scrapings and contact lenses were positive for Klebsiella oxytoca,
Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Pseudomonas spp. The
treatment with topical levofloxacin and 25% (w/v) γ-irradiated honeydew honey
solution was effective and the patient achieved final best corrected visual
acuity of affected eye. In addition to positive clinical outcome, honeydew
honey was shown to be highly effective in vitro against ocular isolates, in
particular S. maltophilia. The minimal inhibitory concentrations for honeydew
honey ranged from 5% to 10%. These results demonstrate that honey is a
promising antibacterial agent in management of corneal ulcers. Moreover, honey
exhibits anti-biofilm and anti-inflammatory properties, and thus becomes an
interesting ophthalmologic agent.
No comments:
Post a Comment